Schizophrenia

Question 1

pathology

Answer 1

too much dopamine

Question 2

diagnostic criteria

Answer 2

1 or more of following:

• Delusions - bizarre delusions or thought control
• Control hallucinations - thoughts can be heard aloud/3rd person or a running commentary

2 or more of following:

• Other hallucinations
• Thought disorder
• Catatonia
• Negative symptoms (apathy, poverty of thought and speech, blunting of affect, social isolation, poor self care)
• Change in personal behaviour - loss of interest, social withdrawal

Question 3

management

Answer 3

bio - atypical first line, BZD for anxiety, procyclidine for EPSE. Depots if needed. Clozapine last resort (agranulocytosis)
Psycho - family therapy, compliance therapy, psychoeducation
Social - social work and housing if needed

Question 4

define schizoaffective disorder

Answer 4

schizophrenic and mood (depressive or manic) symptoms

Question 5

define delusional disorder. when is typical onset

Answer 5

delusion for at least 3 months with only symptom. Typical onset is middle age.

Question 6

drugs that can cause psychosis

Answer 6

alcohol, amphetamine, cocaine, inhalants, corticosteroids, anticholinergics, anti-parkinsons drugs

Question 7

differentials for schizophrenia

Answer 7

manic episode with psychosis, depression with psychosis, delirium, substance induced, temporal lobe epilepsy