Schizophrenia Flashcards
How much of the population does schizophrenia affect
More than 1%
Schizophrenia is a _______ brain disorder
Chronic
What can symptoms of schizophrenia include
Delusions, hallucinations, trouble with thinking and concentration, and lack of motivation
Onset of schizophrenia?
Early 20s. Men a little younger, women a little later
What are the subtypes of schizophrenia?
Paranoid, disorganized, catatonic, undifferentiated, residual
What does the Diathesis-Stress Model of Mental Illness mean?
That a person is born with a certain predisposition and then a stressor comes alone and triggers it once the stage is set.
Diathesis: sets the stage; what you’re born with
Stress: something happens to trigger it
first degree biologic relatives of an individual with schizophrenia have a ____ times greater risk for schizophrenia than the general population
10
The neuro-anatomic findings with a schizophrenic are similar to those of what type of patient?
Dementia
What is the monoamine hypothesis of mental illness
Changes in the levels of monoamine neurotransmitters (5-HT, NE, EPI, DA) cause mental illness
There is too much ________ with schizophrenia
Dopamine
What are positive symptoms
Things added
What is a hallucination
Actually feeling SENSATION without physical stimulation. It can involve and of the five senses
What types are hallucinations usually
Visual or auditory
What are delusions
Fixed false beliefs that you cannot change
What are negative symptoms
Things taken away
What are examples of negative symptoms?
Affective flattening or blunting, ambivalence, alogia, avolition, anhedonia
What is the neurocognitive impairment diagnostic criteria
Memory short and long term, vigilance or sustained attention, verbal fluency, executive functioning, disorganized behavior, disorganized thinking
What are internal senses
Biochemical and emotional
What are external senses
Sight, sound, touch, taste, smell
What does treatment focus on in the acute illness period
Alleviation of symptoms
What are things that go on during the acute illness period
Behaviors may be both confusing and frightening, less able to care for basic needs, functioning at school and work deteriorates, dependence on family and friends increases
What stage is the treatment intense
Stabilization period
What goes on during the stabilization period
Symptoms become less acute but may be present, treatment is intense, medication regimen is established, being to adjust, socialization begins to increase and rehabilitation begins ideally
Ideally when does socialization begin to increase and rehabilitation begin
Stabilization period
What is typically the trigger to a relapse
Noncompliance with medication regimen
What does the maintenance and recovery period focus on
Focuses on regaining the previous level of functioning and quality of life by using medication management and family support and involvement
What are symptoms related to problems in information processing often called
Cognitive deficits
What type of commands to schizophrenic patients often have difficulty with?
Multiple step commands because they use concrete instead of abstract thinking
What type of thinking do schizophrenic patients use? Especially in acute episodes
Concrete rather than abstract thinking
For a schizophrenic patient to make the appropriate decision what does the nurse need to do?
Provide information as clearly and concretely as possible with simple language in short , easily understood phrases
What are some thought content descriptors
Thought broadcasting, thought insertion, ideas of reference, and magical thinking
What is alogia
Reduced fluency and productivity of thought and speech
What is avolition
Withdraw and inability to initiate and persist goal-directed activity
What is anhedonia
Inability to experience pleasure
What is a grandiose delusion
The belief that one has exceptional powers, wealth, skill, influence, or destiny
What is a nihilistic delusion
The belief that one is dead or a calamity is impending
What is a persecutory delusion
The belief that one is being watched, ridiculed, harmed, or plotted against
What is a somatic delusion
Beliefs about abnormalities in bodily functions or structures
What are the different types of delusions
Grandiose, nihilistic, persucatory, somatic
Are auditory or visual hallucinations more common?
Auditory
What prevents a person with schizophrenia from enjoying activities
Anhedonia
Extremely detailed and lengthy discourse about a topic
Circumstantial
The topic of conversation changes repeatedly and rapidly, generally after just one sentence or phrase
Flight of ideas
Absence of the normal connectedness of thoughts, ideas, and topics; sudden shifts without apparent relationship to preceding topics
Loose associations
The topic of conversation is changed to an entirely different topic that is a logical progression but causes a permanent detour from the original focus
Tangentiality
String of words that are not connected in any way
Word salad
What are the first symptoms of psychosis
Abnormal perception: inaccurate identification and interpretation of stimulus
Is there a identifiable external or internal stimulus with hallucinations?
No
What can cause auditory hallucinations
Excessive noise or sensory deprivation
What are some environmental factors that can stimulate visual hallucinations
Reflective objects like tv screens, photos frames, fluorescent lights
What is affect? What are ways to describe?
Expressed emotions; describe as broad, restricted, blunted, flat, or inappropriate
What are some maladaptive movements with schizophrenia
Catatonia, abnormal eye movements, grimacing, apraxia/echopraxia, abnormal gait, mannerisms, extrapyramidal side effects of psychotic medications
what are some behaviors that cause socialization problems?
Inability to communicate coherently, loss of drive and interest, deterioration of social skills, poor personal hygiene, paranoia, stigma
What is neurocognitive impairment often seen as?
Disorganized symptoms
What are disorganized symptoms?
Confused speech and thinking patterns, disorganized behavior
What is echolalia
Repetition of words
What are examples of disorganized thinking
echolalia, circumstantial, loose associations, tangential, flight of ideas, word salad, clang association, pressured speech
What are examples of disorganized behavior
Aggression, agitation, catatonic excitement, echopraxia, stereotypy, hypervigilance, waxy flexibility
What is waxy flexibility
Posture held in odd or unusual way
What is hypervigilance
Sustained attention to external stimuli
What is echopraxia
Imitation of others movements
First priority is always _______
Safety
Why do these people have a high risk lifestyle
Sedentary, smoking, or dietary habits; obesity resulting in diabetes, hypertension, coronary artery disease
What do antipsychotics do
Block dopamine transmission in the brain
Are first generation or second generation antipsychotics more efficacious and safer?
Second generation antipsychotic drugs appear to be more efficacious and safer than conventional antipsychotics
How long does it take antipsychotic drugs to effect a change in symptoms
1-2 weeks. The delay in outcome is why people stay in hospital to see if they are working
Why would a antipsychotic be used in a emergency situation for a patient who was acting out?
Sedating effect. This is a chemical restraint and must be documented
What are some extrapyramidal side effects
Parkinsonism, akathisia, tardive dyskinesia, orthostatic hypotension, hyperprolactactinemia, weight gain, sedation, new onset diabetes, cardiac arrhythmias, agranulocytosis
Is tardive dyskinesia a early or late appearing extrapyramidal side effect for antipsychotic meds?
Late
What does tardive dyskinesia involve
Irregular, repetitive involuntary movements of the mouth, face, and tongue, including chewing, tongue protrusion, lip smacking, Puckering of the lips, and rapid eye blinking
Is tardive dyskinesia reversible?
No it is irreversible
What is neuroleptic malignant syndrome
A life threatening condition that can develop in reaction to antipsychotic meds. Patients develop severe muscle rigidity and an elevating temperature
What are recognizing symptoms of neuroleptic malignant syndrome
Elevated temperature, changes in level of consciousness, leukocytosis, elevated creatinine phosphokinase, elevated liver enzymes or myoglobinuria
Nursing interventions with neuroleptic malignant syndrome
Stop administration of offending medications, monitor vital signs, reduce body temperature, and safety to protect muscles
What are supportive measures with neuroleptic malignant syndrome
IV fluids, cardiac monitoring, and Dantrolene (dopamine agonist) to make body know there is still some dopamine
What are symptoms of anticholinergic crisis
Elevated temperature, dry mouth, decreased salivation, decreased bronchial, nasal secretion, widely dilated eye (hot as a hare, blind as a bat, mad as a hatter, dry as a bone, red as a bee); confusion, hallucinations
What is anticholinergic crisis
Potentially life threatening, anticholinergic delirium, can occur with patients who are taking several medications with anticholinergic effects
Does anticholinergic crisis go away?
Yes it is self limiting; 3 days
Treatment for anticholinergic crisis
Discontinuation of medication; Physostigmine 1-2 mg IV, an inhibitor of cholinesterase, improves in 24-36 hours; gastric lavage; charcoal, catharsis
What should you teach patients about delusions and hallucinations
That they are symptoms of illness and part of the disorder
What does inpatient care focus on
Stabilization
What does emergency care focus on
Crisis
What does community care focus on?
This is where most of the care happens
Absorption of antipsychotic meds
Variable 30-60 minutes
Where is metabolism of antipsychotic drugs?
Liver—look at liver function test!
Is excretion of antipsychotic drugs fast or slow?
Slow
What blood level does a patient with schizophrenia who is taking clozapine need to monitor weekly
WBC because agranulocytosis can develop with the use of all antipsychotic drugs but most likely to develop with clozapine use
A patient who has been taking clozapine for 6 weeks visits the clinic complaining of fever, sore throat, and mouth sores. What would the nurse suspect?
Agranulocytosis
What are the 1st gen/typical antipsychotics
Chlorpromazine
Thioxanthenes
Haloperidol
What are the 2nd gen/atypical antipsychotics
Clozapine Olanzapine Risperidone Ziprasidone Aripiprazole Quetiapine