Schizophrenia 2 Flashcards
State some facts about schizophrenia.
It is a mental disorder that affects male and females. It is usually diagnosed using the DSM from ages 15-35
State one way the DSM classifies schizophrenia
Delusions, hallucinations, negative symptoms, catatonic behaviour, disorganised speech for 1 month
What are the 2 positive symptoms?
Delusions (false beliefs, paranoid, inflated beliefs or power or influence)
Hallucinations (false perceptions, visual, auditory)
What are the 2 negative symptoms of schizophrenia?
Avolition (a reduction in goal directed behaviour)
Speech Poverty (reduction in fluency and productivity)
What are the 3 biological explanations for schizophrenia?
Genetics, The Dopamine Hypothesis, Neural Correlates
What does genetics suggest schizophrenia is caused by?
Hereditary, polygenic, candidate genes e.g. PCMI
What are the 3 genetic studies?
Family studies, twin studies, adoption studies
Explain family studies.
Schizophrenia is more common between those biologically related than not biologically related. Closer related = higher risk
Explain twin studies
Monozygotic twins have a higher concordance for schizophrenia that dizygotic twins
Explain adoption studies
Separates the influence of genetics and the environment, as can study biologically related individuals who were reared differently
Name 2 evaluation points for genetics
Research support (46% concordance), nature (ignores environmental factors)
Define reliability
The consistency of a measuring tool for diagnosis of schizophrenia
What are the two types of reliability?
Test - retest reliability and inter rater reliability
Explain test - retest reliability.
Multiple doctors have to diagnose a patient at different times to ensure not labelled with a diagnosis that changes
Explain inter rater reliability
The concordance between two doctors diagnosis
Name 2 evaluative points for reliability.
Cultural differences (US69% V UK 2%)
Research support (12 hospitals, 7-52 days)
Define validity
The extent to which a diagnosis is accurate and meaningful
Name 3 evaluative points for validity
Gender bias (criteria, stereotypes, mentally healthy adult), symptom overlap (incorrect diagnosis), co-mobility (Two or more conditions occur, depression 50%)
Explain the dopamine hypothesis
Schizophrenics have too much dopamine in their synapse, so more bind with D2 receptors = easily fired = positive symptoms
What are the two versions of the dopamine hypothesis?
Hyperdopaminergia (excess = positive)
Hypodopaminergia (lack = negative)
What are the 2 evaluative points for the dopamine hypothesis
Research support - post mortem show increase in dopamine and D2 receptors in brain, individual differences - only 1/3 effected by drugs
What are the 5 neural correlates?
Ventricular space, avolition/ventral striatum, amygdala, superior temporal gyri, pre frontal cortex
Explain the role of ventricular space on schizophrenia.
Have more ventricular space = fluid filled cavatines = lighter brain
Explain the role of the pre frontal cortex on schizophrenia
Lower activity in the pre frontal cortex causes delusions