Schizophrenia Flashcards
What is a positive symptom
An additional experience beyond those of ordinary existence
What’s a negative symptom
A loss of usual abilities and experiences
What are some examples of positive symptoms
Hallucinations- unusual sensory experiences that have no basis in reality , eg auditory or visual hallucinations
Delusions - false beliefs that have no basis in reality , they can make ppl w schizophrenia behave in ways that only make sense to them
What are examples of negative symptoms
Avolition - severe loss of motivation to carry out everyday tasks and reaching goals eg lack of persistence in work
Speech poverty - reduction in the amount of quality and speech
How does classification of schizophrenia work
2 major systems for classification of schizophrenia: ICD - 11 used in the uk and he must show 2+ negative symptoms for one month or longer. However it also recognises sub types of schizophrenia like paranoid and catatonic schizophrenia
DSM - 5 - used in USA , must show one positive symptom for at least a month. Doesn’t categorise further into subtypes
How does reliability and validity correlate to SZ
Reliability refers to whether we can gain consistent results when classifying and diagnosing Sz.
Validity refers to the accuracy, the extent to which we are measuring what we intend to measure.
What is the study into reliability ans validity of SZ
Cheniaux asked two psychiatrists to diagnose the same 100 patients using DSM and ICD. One diagnosed 26 according to DSM and 44 according to ICD . The other diagnosed 13 according to DSM and and 24 ICD. Showing poor inter rater reliability and poor reliability in the diagnosis of SZ
What’s symptom overlap
Co morbidity
2 or more conditions share similar symptoms
Co morbidity - 2 illnesses occur at the same time
What’s a problem , of reliability and validity
:( there’s often symptom overlap where 2 + conditions share similar symptoms, eg both SZ and depression involve neg symptoms like Avolition , weakening the validity and reliability of the classification and diagnosis of sz, dr may then not be diagnosing SZ properly
:( co morbidity where 2 illness occur at same time, in research patients who had SZ also had depression and some other patients who had SZ also had ocd, questioning whether sz is a separate disorder or not and it causes reliability problems bc there may be confusion over which disorder is being diagnosed
What are genetic biological explanations for SZ
Genetic states that SZ is hereditary and passed on from one generation to the next through genes which increases a persons vulnerability to developing sz
There are 108 maladaptive candidate genes including PCM1 which increases vulnerability to Sz
Neural biological explanations to Sz
-abnormalities within the brain may be associated with the development of Sz
-a correlate of Sz is enlarged ventricles which cause damage to brain areas and this damage is associated with negative symptoms of Sz
What’s another correlate to Sz (enlarged ventricles was the first one)
Dopamine hypothesis- the brains neurotransmitters work diff in the brain of a patient w Sz , dopamine is very involved in Sz patient brains
Hyperdopaminergia in sub cortex - high lvls dopamine in Broca’s area associated with auditory hallucinations
Hypodopaminergia in cortex - low lvls dopamine in prefrontal cortex have been associated with negative symptoms like Avolition
Biological explanation of Sz Ao3
biological determinism, states theory is controlled by internal factors like high or low lvls of dopamine which can cause auditory hallucinations or Avolition. Neglecting role of free will leaving indivs feel as tho they have no control over their schizophrenic behaviour . Limiting the biological explanation for Sz
A strength is that it has practical applications, the theory states Sz can be caused due to dopamine imbalances which had lead to the treatment of drug therapies to treat these imbalanced lvls and reduce their symptoms of hallucinations and delusions. Increasing the effectiveness of the biological approach to wards Sz
What do agonists do and antagonists do
Increase activity of a neurotransmitter at a synapse
Reduce the activity of a neurotransmitter at a synapse
Antipsychotic drugs
Are the most common treatment for Sz, some patients can take them temporality whereas some for their whole life