Schizophrenia Flashcards

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1
Q

What is schizophrenia?

A

A form of psychosis (where people loose some or all contact with reality). It is a splitting of the mind and the patient has fragmented thinking. Illness of the thought process.

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2
Q

What does the DSM say about the diagnosis of Schizophrenia?

A

Two or more of the following symptoms must be displayed during a month period:
-Delusions
-Hallucinations
-Disorganised speech
-Grossly disorganised or catatonic behaviour
-Negative symptoms

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3
Q

What are the positive symptoms of Schizophrenia?

A

Hallucinations and delusions

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4
Q

What are the negative symptoms of schizophrenia?

A

Speech poverty and avolition

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5
Q

What are hallucinations?

A

Unusual sensory experiences. False perceptions with no basis in reality eg hearing voices

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6
Q

What are delusions?

A

False beliefs that are firmly held despite being illogical eg beliefs about being a victim of conspiracy

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7
Q

What is speech poverty?

A

Where there are changes in patterns of speech. Reduction in the amount or quality of speech and delay of responses.

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8
Q

What is avolition?

A

Finding it difficult to begin or keep up with goal directed activities.

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9
Q

What are positive symptoms?

A

Behaviours/ experiences added on to behaviour.

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10
Q

What are negative symptoms?

A

Behaviours that are absent/ lacking eg hygiene, loss of emotion and social withdrawl

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11
Q

What is co-morbidity?

A

When a person has two disorders eg schizophrenia and depression

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12
Q

What is symptoms overlap?

A

When two or more conditions share the same symptoms, which may affect whether you get the correct diagnosis.

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13
Q

What was the aim of Rosenhan’s study?

A

To investigate how situational factors affect a diagnosis of schizophrenia.

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14
Q

Method of Rosenhan’s study

A

8 confederates acted as pseudopps going to 12 diff hospitals. Real pps was hospital staff. Pseudopp called hospital for appointment and when arrived they complained of hearing voices which were unclear, unfamiliar and of the same sex as them. Pseudopps gave false names and symptoms but real life histories. Once on the ward, pseudopps stopped pretending symptoms, behaved normally and wrote observations. They were discharged only when they convinced staff they were sane.

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15
Q

Conclusion of Rosenhan’s study

A

Psychiatrists cannot reliably tell the difference between an insane and sane person, calling into question the reliability of a Sz diagnosis. Normal behaviour was interpreted as abnormal to support their idea that pseudopatients had a mental illness. This suggests that validity of psychiatric diagnoses was low and the DSM was flawed.

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16
Q

Results of Rosenhan’s study

A

On admission, staff diagnosed 7 pseudopatients with Schizophrenia, and one with manic- depression. Staff never detected their sanity. Nurses reported their behaviour as showing „no abnormal indications” but did interpret their behaviour in the context of their diagnosis. Avg hospital stay was 19 days. All pseudopatients were discharged with diagnosis of Sz in remission. 35 real patients detected sanity.

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17
Q

What did Rosenhan’s find the issues were with diagnosis?

A

Not accurate as did not detect 8 patients were fake patients.
1 out of 8 patients were diagnosed with bipolar even though same symptoms given to doctor.

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18
Q

What impact did Rosenhan have on diagnosis?

A

Made changes to DSM so it has better accuracy and consistency
Better attitude towards mental health in society

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19
Q

What is an reliability (strength surrounding diagnosis of Sz)?

A

Reliability which means how consistent the diagnosis is between clinicians and diagnostic systems. Rosenhan found all 8 pseudopatients were diagnosed with a mental illness which shows there is consistency within clinicians. This is a strength in diagnosis of Sz because it shows inter rater reliability in diagnosis. This is supported by Osorio et al who reported excellent reliability for Sz diagnosis, using the DSM 5. They found inter rater agreement of +0.97 and test retest reliability was +0.92. Diagnosis of Sz is consistent when using DSM.

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20
Q

Cultural bias in diagnosis

A

Some cultures do not see hearing voices as a negative experience. In Afro Caribbean societies they hear voices from their ancestors and this would not be regarded as Sz. They see it as a gift from God. This is supported by Afro Caribbean British Men are up to ten times more likely to receive a diagnosis as white British Men, probably due to over interpretation of symptoms of Uk psychiatrists. This means Afro Caribbean men living in the UK appear to be discriminated against in a culturally- biased diagnostic system.

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21
Q

Validity in diagnosis of Sz

A

Whether diagnosis is accurate or not. Criterion validity involves seeing whether diff procedures used to assess the same individual’s arrive at the same diagnosis. Cheniaux et al shows diagnosis of Sz has low validity. Two psychiatrists independently assessed the same 100 clients using ICD and DSM. 68 were diagnosed w Sz with ICD and 39 with the DSM, which shows 29 where diagnosed differently. Sz is either over or under diagnosed, because there diff diagnosis rates between the two diagnostic tools, which suggests criterion validity is low.

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22
Q

Symptom overlap in diagnosis

A

There is an overlap between symptoms of Sz and other conditions. This makes diagnosis tricky as Sz may not exist as a singular condition and if it does it is hard to diagnose.

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23
Q

Tienari et al study (genes)

A

Adopted children of biological mothers with Sz were more likely to develop Sz then adopted children with mothers who did not have Sz. Supports genetic link to Sz

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24
Q

Percentage of developing Sz if parents have it?

A

6%

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25
Q

Percentage of Sz if your biological siblings have Sz?

A

9%

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26
Q

% of developing Sz if your identical twin has it?

A

48%

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27
Q

Schizophrenia is polygenic?

A

There is not a candidate gene. There is a number of genes which code for dopamine involved. 108 variations of genes associated with Sz.

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28
Q

Sz is aetiologically heterogenous?

A

Different combinations of factors including genetic factors can lead to the condition.

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29
Q

The role of mutation in genes

A

Schizophrenia can also have a genetic origin in the absence of family history.
May be mutation in parental DNA which can be caused by radiation or poison.

30
Q

Evaluation for genes as an explanation for Sz

A

+ Strong evidence to support
Family studies such as Gottesman (1991) shows someone with a parent with Sz has a 6% of developing Schizophrenia.
Adoption studies (Tienari)
This shows people are more vulnerable to Sz because of their genetics.

-Explanation does not consider environmental factors.
Sz can be caused by stress, drugs and birth complications, which are all environmental influences.
Morkved et al found 67% of people with Sz and related psychotic disorders reported at least 1 childhood trauma as opposed to 38% of a match group with non psychotic mental health issues.
Genes alone cannot provide a complete explanation for Sz.

31
Q

What is the neurotransmitter involved in Schizophrenia?

A

Dopamine

32
Q

What is the original dopamine hypothesis (hyperdopminergia)?

A

Believes there is high dopamine activity in the sub cortex which is associated with hallucinations and speech poverty. There is a high level of D2 receptors in the pathways linking from sub cortex to Broca’s area. This explains specific symptoms such as speech poverty and auditory hallucinations.

33
Q

What is the updated version of the dopamine hypothesis (hypodopaminergia)?

A

It suggests people with Sz have abnormally low levels of dopamine in the prefrontal cortex. Can explain negative symptoms. It is thought cortical (outermost layer of brain made of grey matter) hypodaminergia leads to hypodopaminergia.

34
Q

Evaluation of neural explanation of Schizophrenia

A

-Not all Sz patients have Sz due to neural reasons. This has been found due to drug treatments not working. Albert and Friedhoff found that some patients show no improvement at all after taking dopamine antagonists. This shows there must be other explanations for Sz because if drugs do not change the behaviour it suggests Sz is not down to neurotransmitters.

-Dopamine may not be the only neurotransmitter involved, there is evidence to suggest Glutamate has a role. Post mortem and live brain scanning studies found raised glutamate in people with Sz. Several candidate genes for Sz are involved in glutamate production or processing. This means a strong case can be made for a role for other neurotransmitters involved for Sz.

35
Q

What are the 2 psychological explanations for Sz?

A

Family Dysfunction and cognitive explanations

36
Q

What is the Schizophrenogenic mother (family dysfunction)?

A

Reichman
Psychodynamic explanation for Sz based on childhood accounts for patients. Many talked of the schizophrenogenic mother who is cold, controlling and creates a family climate characterised by tension. Leads to distrust which later develops into paranoid delusions.

37
Q

What is the Double-bind theory?

A

Bateson
Emphasised the role of communication style within a family. Child fears doing the wrong thing but they receive mixed messages on what it is and feel unable to comment on the unfairness of the situation. When they get it wrong they’re punished with a withdrawal of love which leaves them with an understanding of the world as confusing- disorganised thinking and paranoid delusions.

38
Q

PARENT BLAMING AO3 (FAMILY DYSFUNCTION)

A

Research linking family dysfunction to Sz is highly socially sensitive and can lead to harmful implications for parents, particularly mothers.

Studies suggest that other factors, such as conflict and poor communication, may contribute to the development of schizophrenia symptoms.

This focus on family dynamics can inadvertently place blame on parents, making them feel responsible for their child’s condition. Mothers, in particular, may experience increased stigma and guilt, as they are often viewed as the primary caregivers.

this blame can exacerbate the emotional burden for families already struggling with the challenges of mental illness, highlighting the need for a more compassionate understanding of the role of family in schizophrenia.

39
Q

SUPPORTING EVIDENCE AO3 (FAMILY DYSFUNCTION)

A

Indicators of family dysfunction, such as exposure to childhood trauma and insecure attachment are significant contributors to the development of schizophrenia (Sz).

Research- 69% of women and 59% of men with Sz have a history of physical or sexual abuse.

These traumatic experiences can disrupt healthy attachment patterns, leading to insecure relationships that may influence the onset and course of schizophrenia. The link between childhood trauma and later mental health issues highlights the impact of family dynamics and early life experiences on psychological well-being.

40
Q

What is dysfunctional thinking (cognitive explanation)?

A

Sz is characterized by disruption to normal thought processing. Reduced thought processing in the central stratium is associated with negative symptoms. Reduced processing of info in the temporal and cingualte gyro associate w hallucinations

41
Q

What is meta representation dysfunction (cognitive explanation)?

A

Meta representation= cognitive ability to reflect on our thought and behaviour which allows insights into our own intentions and goals. Allows us to interpret the action of others. Dysfunction in meta representation would disrupt our ability to recognise our own actions and thoughts and being carried out by ourselves rather then someone else. Explains hallucinations and delusions.

42
Q

AO3 PROXIMAL EXPLANATION (COGNITIVE)

A

One limitation of cognitive explanations is that they only explain the proximal origins of symptoms.
Cognitive explanations for schizophrenia are proximal explanations because they explain what is happening now to produce symptoms - as distinct from distal explanations which focus on what initially caused the condition.

43
Q

What is the biological treatment for Sz?

A

Drug therapy (Antipsychotic drugs) which allows for Schizophrenics to have some normal functioning. They are given when the individual has their first episode of Schizophrenia. Drug therapy contains chemicals which works on the brains neurotransmitters. They work by suppressing the hallucinations and delusions, as they work on the dopamine system. Can be used long term or short term.

44
Q

What are the two types of antipsychotic drugs?

A

Typical and atypical

45
Q

What are typical drugs? (Older generation drugs)

A

Works only on dopamine and lowers its bad side effects.
Works best on positive side effects.

46
Q

What is a type of typical drugs?

A

Chlorpromazine which works by acting as an antagonist in the dopamine system to reduce hallucinations. Causes side effects such as problems with sexual function, blank facial expression.

47
Q

What are atypical drugs? (Newer gen drugs)

A

Works on dopamine and other neurotransmitters eg glutamate

Fewer side effects

Better for negative symptoms

48
Q

What is an example of an atypical drug?

A

Clozapine

Binds to dopamine, serotonin and glutamate receptors.
Improves mood and cognitive function
Causes dizziness, confusion and nausea.

49
Q

Evaluation for whether drug therapy works for schizophrenia.

A

+Drug therapy works on schizophrenics quickly and are cost effective.
This means that people who suffer can quickly get back to society. Drugs are cheaper than other treatments such as CBT, as they take a few sessions to make an impact. This benefits the society and individual in many ways.

-Drug therapy has side effects. Short term side effects include dizziness and weight gain. Long term side effects include Tardive Dyskinesia which is involuntary, repetitive body movements, which may include grimacing, sticking out the tongue due to dopamine supersensitivity.

-It is unclear how these antipsychotic drugs work. The use of these drugs work in line with the original dopamine hypothesis so drugs decrease the amount of dopamine. There is evidence that this explanation is not correct and dopamine levels is lower in the prefrontal cortex which these drugs do not work for.

50
Q

What is CBT (Psychological treatment for Sz)?

A

It is a talking therapy which aims to identify irrational thoughts and try to change these to more rational thoughts.
Therapists sit with the Schizophrenic and helps them to understand their hallucinations and delusions are not real. They make them normalised.
They may explain the biological functioning of the thoughts and how their symptoms are due to malfunctioning of the speech centre in the brain.

Does not eliminate hallucinations and delusions but does control them!!!

51
Q

Why would drug therapy alongside CBT be beneficial?

A

Drugs suppress delusions as they work on the dopamine system. They tackle symptoms quicker.

52
Q

Evaluation for CBT

A

-Therapy has been criticised for being time consuming and demands a significant commitment from patients. The process involves regularly attending therapy sessions and completing homework assignments outside of therapy. This investment of time and effort can be challenging for individuals already struggling with the challenges of Sz.

-The quality of research conducted on CBT and Sz is questionable as a range of techniques and symptoms are looked at. Thomas (2015) stated that different studies focused on different CBT techniques and people with different symptoms. Because symptoms and techniques vary widely overall, modest benefits of CBT for Sz may conceal a range of effects of different techniques on different symptoms. Using different techniques and exploring different symptoms makes it difficult to say how effective the treatment is.

53
Q

Family therapy as a psychological treatment of Sz

A

Aims to improve the communication with the family and reduce stress of living with Sz. Allows the family to understand the illness, as they receive information about it and have the chance to ask questions. The therapist actively encourages discussion about what it is like to live with a a family member and how to support them. This allows them to come to terms with the patients behaviour as Sz can be frightening. Allows everyone’s voices to be heard, reducing tension.

Takes place over many sessions and usually in the patients home, sometimes as a group.

Reduces likelihood of relapse. Particularly used when Sz has been caused by family dysfunction, as it allows the family to work together and build on their relationship.

54
Q

burbach’s Model of Practise

A

7 stages families work through with therapist to help build an understanding of Sz and learn to support the patient.

55
Q

Phase 1-2 of burbach’s model of practise

A

Sharing info and identity issues families can and cannot offer

56
Q

Phases 3-4 of Burbach’s

A

Learn and encourage mutual understanding and creating a safe space for families top express their feelings. They look at and tackle the unhelpful patterns of interaction.

57
Q

Phases 5, 6 and 7 of Burbach’s

A

Skills training eg stress management techniques.

58
Q

What did Pharoah et al identify?

A

A range of strategies that family therapists use to try and improve the functioning of a family that has a member w Sz.

  1. Reduces negative emotions eg guilt within the family, to lower the stress as stress causes relapse
  2. Improves families ability to help- helps families to form a therapeutic alliance. Creates balance between care of schizophrenic and their own life.
59
Q

How good is family therapy for Schizophenics?

A

+Benefits the whole family, not just the patient. It lessens the negative impact on the family, as they have developed an understanding of the illness. This strengthens the family unit and the ability for the family to support. It has wider benefits beyond the obvious positive impact on the patient.

-Is family therapy more beneficial for economics or the family? It reduces relapse rates and helps families support and provide majority of the care for the schizophrenic patients, which saves a lot of money for the NHS. It also provided therapeutic benefits for the family. This means there is economic gain, as the patient and family are being supported.

60
Q

What are similarities between biological and psychological treatments of Sz?

A

Both therapies require the patient engage in the therapeutic process. With drug therapy, patient needs to constantly take their medication. In CBT, the patient needs to engage with their therapist

Both aim to reduce symptoms however they do not cure the disorder. Drug therapy adresses an imbalance in neurotransmitters and CBT adresses fixed false beliefs.

61
Q

What are differences between between psychological and biological treatments of Sz?

A

Drug therapy can be done alone but CBT is done with a therapist present.

CBT does not result in potential side effects whereas antipsychotic medication may result in extra pyramidal symptoms.

62
Q

What are token economies?

A

A form of behaviour modification that works on reward systems. Desirable behaviours are encouraged via rewards when in hospital.
Based on operant conditioning

63
Q

How do token economy programmes work for those with Sz?

A

While in hospital, every time a schizophrenic does a task they are given a token.
Tokens= secondary reinforcers so can be exchanged for food (primary reinforcers) or privileges.
Targeted behaviours decided for every patient (need to know the patient). Tokens given straight after behaviours.

64
Q

The rationale for token economies

A

A prolonged time in hospital can develop into bad habits eg poor hygiene.
Matson et al says Token economy programmes tackle: personal care, condition related behaviours and social behaviour. Improves Schizophrenics quality of life.

65
Q

Do token economy programmes work for managing schizophrenia?

A
  • Token economies are difficult to continue once the schizophrenic has left hospital. This is because target behaviours cannot be closely monitored and tokens cannot be administered immediately. This will mean that behaviours that were being managed in the hospital may come back once they have left. This suggests token economies may not work long term.

-There are ethical issues because it gives the professional a considerable amount of power to control the behaviour of the schizophrenics. This inevitably involves imposing one person’s norms to others, which is especially problematic of target behaviours that are not identified sensitively. For example, someone who likes to look scruffy and get up late might have these personal freedoms removed. This could restrict the availability of pleasures such as sweets to those who are severe, so will have a worse time on these programmes. Legal action by families who see their relatives in this position have been a major factor in the decline in the use of token economies. This means the benefits of toke economies may be outweighed by their impact on personal freedom.

66
Q

What is the interactionist approach also known as?

A

Biosocial approach as it acknowledges there are biological, psychological and social factors in the development of Sz which interact with eachother.

67
Q

Older understanding of diathesis stress model.

A

Diathesis (vulnerability) is entirely genetically, the result of a single schizogene. If you do not have these gene no stress would lead to Sz.

Schizogene + schizophrenogenic mother = Sz

68
Q

Modern understanding of diathesis stress model

A

There is not 1 schizogene and Sz is polygenic
Psychological factors can cause vulnerability eg childhood trauma. It can alter the brain eg the hypothalamic pituitary adrenal system can become overactive due to trauma making the individual vulnerable to stress later.

Psychological factor + stress = Sz

69
Q

Modern diathesis stress model- Drug Use

A

Cannabis is a stressor as interferes with dopamine

Genes/ childhood abuse + drugs = Sz

70
Q

Interactions treatment of Sz

A

Turkington- Tackles both psychological and biological factors in Sz. Antipsychotic medicine and psychological treatments

Both treatments = interacationist treatments

Not possible to treat Sz with 1 type of treatment

71
Q

Evaluation of interactionist approach to Sz

A

+Has been applied to treatments of Sz. Combining drug treatment and the psychological therapies enhances the effectiveness of treating Sz. In a study they randomly allocated 315 pps to:
1) medication and CBT
2) medication + supportive counselling
3) medication only (control group)
Pps in groups 1 and 2 had lower symptom levels
This means there is a clear practical advantage to adopting an interactionist approach to Sz in terms of superior treatment outcomes.

  • Multiple genes increase vulnerability, each with a small effect on it’s own- no schizogene. Research now believes stress can also include biological factors. Houston et al found childhood sexual trauma emerged as a major influence on underlying vulnerability to Sz and cannabis use as a major trigger. There are multiple factors involved that interact.