Schizophrenia Flashcards
What is the characteristic of Sz?
Schizophrenia does not have a single defining characteristic: it appears to be a collection of unrelated symptoms.
What are the two major systems for the classification of mental health disorders?
Internation Classification of Disease (ICD-11)- used in the UK
Diagnostic and Statistical Manual (DSM-5)- used in the USA
Differences between ICD-11 and DSM-5.
- In the ICD-11, two or more negative symptoms, for one month or longer are sufficient for diagnosis, WHEREAS in the DSM-5, one positive symptom must be present for at least one month for a diagnosis.
- The ICD-11 recognises subtypes of schizophrenia. Paranoid schizophrenia is characterised by powerful delusions and hallucinations and catatonic schizophrenia involves problems with a patient’s movements , e.g. they may be immobile for long periods of time, WHEREAS DCM-5 does not categorise schizophrenia further into subtypes.
What is a positive symptom?
An additional experience beyond those of ordinary existence.
Give two examples of positive symptoms.
Hallucinations and delusions.
Explain hallucinations.
Unusual sensory experiences that have no basis in reality, they can affect any sense. For example:
- Auditory hallucinations (hearing voices that aren’t present) or
- Visual hallucinations (seeing objects that aren’t present)
Explain delusions.
Irrational/false beliefs that have no basis in reality, they can make people with schizophrenia behave in ways that make sense to them but may be bizarre to others.
Examples of delusions:
- Delusions of persecution, which is the false belief that you are being harassed e.g. by the government or
- Delusions of control, which is where you have a false belief that you are being controlled by something external e.g. by aliens.
What is a negative symptom?
A loss of usual abilities and experiences.
Give two examples of negative symptoms.
Avolition and speech poverty.
Explain avolition.
Severe loss of motivation to carry out everyday tasks and difficulty to begin or keep up with goal directed activity.
Andreason (1982) identified three signs of abolition; poor hygiene and grooming, lack of persistence in work or education and lack of energy.
Explain speech poverty.
A reduction in the amount and quality of speech, this is sometimes accompanied by a delay in the sufferers verbal responses during conversation or a lack of fluency.
Define diagnosis.
The identification of the nature of an illness or other problem by examination of the symptoms.
e.g. someone reporting hearing voices.
Define classification.
The action or process of classifying something: the classification of disease according to symptoms.
e.g. a symptom of Sz is hallucinations.
Explain what is meant by reliability in diagnosis and classification of schizophrenia.
- Reliability refers to consistency.
- This refers to whether we can gain consistent results when classifying and diagnosing Sz.
- Therefore, the extent to which different classification systems agree upon how schizophrenia should be classified and the extent to which two or more health professionals would agree on the same diagnosis, regardless of time period or culture, is measured by inter-rater reliability.
Explain what is meant by validity in diagnosis and classification of schizophrenia.
- Validity refers to accuracy, the extent to which we are measuring what we intend to measure (schizophrenia).
- For example, are the classification systems accurately outlining the signs and symptoms of schizophrenia and are health professionals accurately diagnosing schizophrenia?
Explain what is meant by reliability AND validity in diagnosis and classification of schizophrenia USING RESEARCH.
- Cheniaux (2009) asked 2 psychiatrists to diagnose the same 100 patients using the DSM and ICD.
- One psychiatrist diagnosed 26 according to DSM and 44 according to ICD.
- The other diagnosed 13 according to DSM and 24 according to ICD.
- This shows poor inter-rater reliability as one psychiatrist diagnosed almost double the amount than the other psychiatrist.
- Also demonstrates poor RELIABILITY in classification of Sz as both psychiatrists diagnosed almost double the number of patients using ICD compared to DSM, which also questions the VALIDITY of the diagnosis.
Define symptom overlap.
Where two or more conditions share similar symptoms.
E.g. both Sz and depression involve negative symptoms such as avolition.
Define co-morbidity.
Where two illnesses/conditions occur at the same time. Sz is commonly diagnosed with other conditions such as depression and/or OCD as they share common symptoms, i.e. lowered mood/motivation. This is a problem as is means Sz may not exist as a distinct condition which may lead to misdiagnosis.
Define gender bias with relevance to Sz.
Since 1980s, more men diagnosed with Sz than women.
Could be because:
- Men= more genetically vulnerable to developing Sz that women.
OR
- Females with Sz typically function better than men, being more likely to work and have good family relationships.
Define culture bias with relevance to Sz.
English people of African origin are more likely to be diagnosed with Sz in the UK.
- Rates in West Indies and Africa are not high, so this cannot be due to genetic vulnerability.
- Higher diagnosis rates in the UK may be because some behaviours are classed as positive symptoms of Sz are normal in African cultures (e.g. hearing voices is part of ancestor communication)
AO3- What is one problem of reliability and classification and the diagnosis of schizophrenia because schizophrenia and depression both have negative symptoms such as avolition?
P- One problem of reliability and validity of the classification and diagnosis of Sz is that there is often a ‘symptom overlap’.
E- This is where two or more conditions share similar symptoms. For example, both Sz and depression involve negative symptoms e.g. avolition.
E- This questions the validity and reliability of the classification and diagnosis of Sz because an individual may be diagnosed with the wrong disorder. This is an issue as doctors may not be diagnosing Sz correctly, and therefore individuals may not receive appropriate treatment.
L- This weakens the validity and reliability in the classification and diagnosis of schizophrenia as it negatively affects its accuracy and consistency.
AO3- What is a further problem with reliability and validity of the diagnosis and classification of Sz using research by Buckley et al?
P- A further problem with the reliability and validity of the diagnosis and classification of Sz is ‘co-morbidity’.
E- This is where two illnesses/conditions occur at the same time. For example, Buckley et al (2009) concluded that 50% of patients diagnosed with Sz also had.a diagnosis of depression and 23% of patients diagnosed with schizophrenia are diagnosed with OCD.
E- This questions the validity and reliability of classification and diagnosis of Sz, because…
L- the two conditions may be better seen as one and doctors may diagnose the wrong conditions.
AO3- Moreover, what is another issue with the validity of diagnosis and classification of Sz because since the 1980s, more men have been diagnosed with Sz than women?
P- Moreover, another issue with the validity of the diagnosis and classification of Sz is gender bias in diagnosis.
E- Since the 1980s, men have been diagnosed with Sz more often than women.
E- This may be because men are more genetically vulnerable to developing Sz than women. However, it could be because females with Sz typically function better than men, being more likely to work and have good family relationships, therefore their symptoms may be masked by good interpersonal skills (Cotton et al).
L- This questions the validity and reliability of the classification and diagnosis of Sz as women who share similar symptoms as men may not receive the same diagnosis as their symptoms may seem mild.
Three explanations of Sz
Biological explanation
Psychological explanations: Family dysfunction and cognitive explanations
Three theories as part of the biological explanation
- Genetic theory
- Neural Correlates:
Brain Structure and Function and 3. Dopamine Hypothesis
Outline the genetic theory.
- The genetic explanation states that schizophrenia is hereditary and passed on from one generation to the next through genes.
- Therefore, a person is born with a genetic predisposition (likelihood) to schizophrenia.
- It is believed that several maladaptive ‘candidate’ genes such as PCM1, are involved (polygenic) which increases an individual’s vulnerability to developing schizophrenia.
- Studies have shown that 108 separate genetic variations are associated in the risk of developing schizophrenia.
- Gottesman (1991) studied 40 twins and found that the concordance rate for monozygotic twins was 48% and only 17% for dizygotic twins.
- Therefore, the closer the genetic link to somebody with schizophrenia, the more chance of developing schizophrenia.
Evaluate the genetic theory as a part of the biological explanation in the development of Sz.
P- Research to support the role of genetics in the development of schizophrenia comes from Tierney.
E- He studied 155 adopted children who had biological mothers with schizophrenia
E- and found that they had a concordance rate of 10% compared to 1% in adopted children without schizophrenic parents.
L- This provides significant support for the role of genetics as an explanation of schizophrenia as the role of Social Learning Theory could not have been a factor as the children were adopted.
What does the idea of neural correlates show?
The idea of neural correlates is that abnormalities within specific brain areas may be associated with the development of schizophrenia.
Brain scanning techniques such as FMRI scans are used to compare the brains of schizophrenics with non-suffers, to identify brain areas that may be linked to Schizophrenia.
Outline brain structure and function as a type of neural correlate.
- One neural correlate of schizophrenia is enlarged ventricles.
- A meta-analysis by Raz and Raz found that over half of individuals tested, with schizophrenia had increased ventricle size compared to a control group.
- Enlarged ventricles are associated with damage to central brain areas and the pre-frontal cortex, this damage is associated with negative symptoms of schizophrenia.
Evaluate brain structure and function as a part of neural correlates as part of the biological explanation for developing Sz.
P- Research to support the role of neural correlates as an explanation for schizophrenia comes from Suddath et al. (1990).
E- He used MRI scans to investigate the brain structure of MZ twins in which one twin was schizophrenic.
E- They found that the schizophrenic twin generally had more enlarged ventricles.
L- This suggests enlarged ventricles do play a role in determining the likelihood of schizophrenia developing.
Outline the dopamine hypothesis as a type of neural correlate.
- The brains chemical messengers (neurotransmitters) appear to work differently in the brain of a patient with schizophrenia.
- In particular, Dopamine (DA) is widely believed to be involved as individuals with sz may release too much dopamine or have a large amount of D2 receptors on the post synaptic neuron.
- Hyperdopaminergia in the subcortex: High dopamine activity in the central areas of the brain such as Broca’s area (responsible for speech production) may be associated with auditory hallucinations. (2 marks)
- Hypodopaminergia in the cortex: Low dopamine activity in the prefrontal cortex (thinking and decision making) have been associated with the negative symptoms of schizophrenia such as avolition. (2 marks)
- It has been suggested that cortical hypodopaminergia leads to subcortical hyperdopaminergia. Both high and low levels of dopamine in different brain regions are involved in different symptoms of schizophrenia.
AO3- What is a strength of the biological explanation (neural correlates) because the theory is based on objective and empirical techniques?
P- A strength of the biological explanation of schizophrenia is that it uses scientific methods.
E- This is because the theory is based on objective and empirical techniques such as gene mapping studies and brain scans such as FMRI
E- which are used to identify specific genes (PCM1) or areas of the brain linked to schizophrenia (enlarged ventricles).
L- Therefore, this increases the overall internal validity of the biological explanation of schizophrenia, thus, raising Psychology’s scientific status.
AO3- What can the biological explanation of Sz (dopamine hypothesis) be criticised for as the theory states individuals are controlled by internal factors ?
P- However, the biological explanation of schizophrenia can be criticised for biological determinism,
E- this is because the theory states that an individual is controlled by internal factors such as high dopamine activity (hyperdopaminergia)
E- in the subcortex which inevitably causes auditory hallucinations.
L- Therefore, it neglects the role of free will, and choice that individuals have; this could leave victims feeling like they have no control over their schizophrenic behaviour.
THINK FURTHER. Furthermore, it be seen as unethical as it can leave victims’ families feeling guilty as they have passed on a gene that has affected their children and it cannot be stopped. Therefore, this limits the biological explanation of schizophrenia.
AO3- What is a strength of the biological explanation of Sz because the principles of the theory can be applied to real life?
P- A strength of the biological explanation of schizophrenia is that it has practical applications.
E- This is because the principles of the theory, that schizophrenia is caused by an imbalance of dopamine has led to the treatment of drug therapies such as typical and atypical antipsychotics.
E- These drugs are effective in treating schizophrenia by balancing levels of dopamine in the patient’s brain and therefore reducing symptoms of schizophrenia such as hallucinations and delusions.
L- Therefore the biological explanation of schizophrenia is an important part of applied psychology as it helps to treat people in the real world.