Schistosomiasis and other flukes Flashcards
Definitive host in schistosomiasis
Humans: Adult worms initiate sexual reproduction
Intermediate host
Snails: Asexual multiplication of larvae
Intestinal schistosomas
S.mansoni
S.japnicum
S.mekongi
S.intercalatum
Urinary schistosoma
S.haematobium
Schistosomiasis with HIV treatment
Praziquantel
may result in dec HIV replication and inc CD4 cells
Stages of disease manifestations
Phase of cercarial invasion
Phase of acute schistosomiasis
Chronic schistomiasis
May be associated with squamous cell carcinoma of the bladder
S.haematobium
May cause CNS schistosomiasis
S.japonicum
Causes transverse myelitis
S.mansoni
S.haematobium
High-level peripheral-blood eosinophilia + positive serologic assay for schistosomal antibodies
Katayama fever
DOC for schistosomiasis
Praziquantel
Associated with cholangiocarcinoma
Chlonorchis sinensis
Opistorchiasis
*ingestion of inadequately cooked freshwater fish
Endemic in sheep-raising countries; CT may show migratory tracks
Fascioliasis
Associated with ingestion of crayfish and freshwater crabs
Paragonimus westermani