Schistosoma Flashcards

1
Q

Schistosoma pathogenic species

A

S. mansoni

S. japonicum

S. hematobium

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2
Q

Schistosoma clinical presentation

A

schistosomiasis, blood fluke infection

S. mansoni and japonicum: colonize portal and GI vessels, form cysts in the tissue and vessels of the region.

  • portal hypertension, ascites
  • abdominal pain
  • bloody diahrrea
  • narrowing of the colon and rectum
  • chronic phase, cirrhosis, liver failure, jaundice

S. hematobium, colonize ureter and bladder vessels

  • bloody urine, hematuria
  • chronic phase, obstruction of ureters/urethra
  • oliguria/anuria
  • hydronephrosis
  • renal failure
  • bladder cancer
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3
Q

Morphology of the schistosoma species

A

the adults are sexually dimorphic, unique among the flukes.
Males small and flat
Females large and round with a long body groove

Eggs in stool are diagnostic for species
S. Mansoni: large lateral spine
S. Japonicum: no spine, smooth eggs
S. Hematobium: large terminal spine

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