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Saviola - Micro Flashcards

1
Q

Produces CAMP factor and synergizes with S.aureus to increase hemolysis/cytolysis

A

P.acnes

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2
Q

Only POX virus to replicate in CYTOPLASM

A

Molluscom contagiosum

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3
Q

Pearly white hemispheric papule with depressed centers. HIV pts

A

Molluscum contagiosa

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4
Q

Double stranded DNA virus in ganglia

A

Varicella Zoster Virus

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5
Q

What is mode of spread of chickenpox in body?

A

Initially hematogenous spread (which is why it is systemic)

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6
Q
  • Unicellular fungi.
  • Reproduce via budding
  • Smooth colonies on solid media (like bacteria)
  • Pseudohyphae
A

Yeasts

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7
Q
  • Multicellular
  • Hyphae
  • Filamentous colonies on media
A

Molds

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8
Q

mold in environment, yeast at body temp

A

medically important fungi

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9
Q

Superficial, cutaneous, or deep?

  • Pityriasis Versicolor
  • Tinea nigra
A

Superficial mycoses

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10
Q

What is Pityriasis tine versicolor caused by?

A

Malassezia furfur

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11
Q

What is Tinea nigra caused by?

A

Hortaea werneckii

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12
Q

Superficial lipophilic skin fungus condition

A

Pityriasis

*spaghetti and meatballs

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13
Q

Dermatophytes prefer which skin layer?

A

keratinized epidermis: skin, hair, nails

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14
Q

Monomorphic fungi that produce keratinases (to use keratin as food source). Cause immune response.

A

Cutaneous mycoses - dermatophytes

*Tinea capitis, cruris, manus, unguium, corporis

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15
Q

Dimorphic fungus with both yeast and mycelial forms

A

Candida albicans

*diaper rash

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16
Q

This one eats glucose and is a problem for diabetics and immune compromised

A

Candida albicans

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17
Q
  • Dimorphic fungus
  • Subcutaneous
  • Accidental implantation
  • Small ulcer–>nodule
  • Lymphatic spread
A

Sporotrichosis

*Sporothrix schenckii

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18
Q

Subcutaneous

A

Sporotrichosis

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19
Q

2 bacteria that cause skin infections

A

Staph aureus

Strep pyogenes

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20
Q

Which skin infecting bacteria matches the following buzz words:

  • clusters
  • coagulase
  • catalase positive
21
Q

Which skin infecting bacteria matches the following buzz words:

  • beta hemolytic
  • bacitracin sensitive
  • pairs and chains
A

S. pyogenes

*group A

22
Q

Protein A

PVL (Panton-Valentine leukocidin)

23
Q

M protein

A

S. pyogenes

  • looks like our proteins, causing cross immune rxn,
  • Strep is typed based on M protein
24
Q

Increases pathogenicity of S. aureus

A

PVL

*creates pores in leukocytes = lysis

25
Name for superficial bacterial infection. Begins as pustule, progresses to vesicle, then crusts like dry honey
Impetigo
26
Impetigo is caused by
S. aureus or Group A Strep
27
Name for bacterial infection in dermis
Ecthyma
28
Ecthyma is caused by
Strep
29
Infected hair follicles are usually caused by _______, unless hot tub folliculitis which is caused by _______.
S. aureus | P. aeruginosa
30
An infection of many hair follicles
furunculosis
31
The bacteria causing furunculosis produce this VIRULENCE FACTOR
PVL *Panton valentine leukocidin
32
Important for PATHOGENESIS of S. aureus because is helps form biofilm and aggregation
Protein A *A for Aggregation
33
Non-bullous impetigo. | Biofilm with polysaccharide matrix
S. pyogenes
34
Microaerophilic bacteria causing inflammation in a cyst
Propionibacterium acnes
35
Acute, severe, rapid bacterial infection of DERMIS and deeper tissues. If systemic, causes fever, sweat, chills
Cellulitis *aureus, pyogenes
36
Superficial cellulitis. S.pyogenes infx. Lymphatics. Dermis and above. FEVER. Face and legs
Erysipelas
37
Only bacteria causing bullous impetigo
S. aureus
38
Systemic bullous impetigo
(SSSS) Staphlococcal Scalded Skin Syndrome
39
TSST-1
Toxic shock superantigen
40
Strep causing toxic shock syndrome produce these exotoxins
M-1 and M-3
41
Caused by a naked icosahedral dsDNA virus
Warts *HPV
42
Toxin related impetigo
Bullous
43
Localized Impetigo
Bullous
44
S. aureus serine proteases
Exfoliative toxins | -Epidermolytic toxin A and B
45
Epidermolytic toxin A and B cleave
Desmoglein-1
46
Phage type of S.aureus that cause Bullous Impetigo
Group II, Phage Type 71
47
Two conditions caused by Epidermolytic toxin A and B
SSSS and Bullous Impetigo
48
T/F: SSSS is just systemic spread of Toxin A and B
True
49
S. aureus phage group causing SSSS
Group II, Phage Type 71

Derm (10 decks)

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