Saviola - Micro Flashcards

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1
Q

Produces CAMP factor and synergizes with S.aureus to increase hemolysis/cytolysis

A

P.acnes

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2
Q

Only POX virus to replicate in CYTOPLASM

A

Molluscom contagiosum

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3
Q

Pearly white hemispheric papule with depressed centers. HIV pts

A

Molluscum contagiosa

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4
Q

Double stranded DNA virus in ganglia

A

Varicella Zoster Virus

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5
Q

What is mode of spread of chickenpox in body?

A

Initially hematogenous spread (which is why it is systemic)

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6
Q
  • Unicellular fungi.
  • Reproduce via budding
  • Smooth colonies on solid media (like bacteria)
  • Pseudohyphae
A

Yeasts

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7
Q
  • Multicellular
  • Hyphae
  • Filamentous colonies on media
A

Molds

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8
Q

mold in environment, yeast at body temp

A

medically important fungi

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9
Q

Superficial, cutaneous, or deep?

  • Pityriasis Versicolor
  • Tinea nigra
A

Superficial mycoses

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10
Q

What is Pityriasis tine versicolor caused by?

A

Malassezia furfur

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11
Q

What is Tinea nigra caused by?

A

Hortaea werneckii

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12
Q

Superficial lipophilic skin fungus condition

A

Pityriasis

*spaghetti and meatballs

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13
Q

Dermatophytes prefer which skin layer?

A

keratinized epidermis: skin, hair, nails

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14
Q

Monomorphic fungi that produce keratinases (to use keratin as food source). Cause immune response.

A

Cutaneous mycoses - dermatophytes

*Tinea capitis, cruris, manus, unguium, corporis

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15
Q

Dimorphic fungus with both yeast and mycelial forms

A

Candida albicans

*diaper rash

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16
Q

This one eats glucose and is a problem for diabetics and immune compromised

A

Candida albicans

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17
Q
  • Dimorphic fungus
  • Subcutaneous
  • Accidental implantation
  • Small ulcer–>nodule
  • Lymphatic spread
A

Sporotrichosis

*Sporothrix schenckii

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18
Q

Subcutaneous

A

Sporotrichosis

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19
Q

2 bacteria that cause skin infections

A

Staph aureus

Strep pyogenes

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20
Q

Which skin infecting bacteria matches the following buzz words:

  • clusters
  • coagulase
  • catalase positive
A

S. aureus

21
Q

Which skin infecting bacteria matches the following buzz words:

  • beta hemolytic
  • bacitracin sensitive
  • pairs and chains
A

S. pyogenes

*group A

22
Q

Protein A

PVL (Panton-Valentine leukocidin)

A

S. aureus

23
Q

M protein

A

S. pyogenes

  • looks like our proteins, causing cross immune rxn,
  • Strep is typed based on M protein
24
Q

Increases pathogenicity of S. aureus

A

PVL

*creates pores in leukocytes = lysis

25
Q

Name for superficial bacterial infection. Begins as pustule, progresses to vesicle, then crusts like dry honey

A

Impetigo

26
Q

Impetigo is caused by

A

S. aureus or Group A Strep

27
Q

Name for bacterial infection in dermis

A

Ecthyma

28
Q

Ecthyma is caused by

A

Strep

29
Q

Infected hair follicles are usually caused by _______, unless hot tub folliculitis which is caused by _______.

A

S. aureus

P. aeruginosa

30
Q

An infection of many hair follicles

A

furunculosis

31
Q

The bacteria causing furunculosis produce this VIRULENCE FACTOR

A

PVL

*Panton valentine leukocidin

32
Q

Important for PATHOGENESIS of S. aureus because is helps form biofilm and aggregation

A

Protein A

*A for Aggregation

33
Q

Non-bullous impetigo.

Biofilm with polysaccharide matrix

A

S. pyogenes

34
Q

Microaerophilic bacteria causing inflammation in a cyst

A

Propionibacterium acnes

35
Q

Acute, severe, rapid bacterial infection of DERMIS and deeper tissues. If systemic, causes fever, sweat, chills

A

Cellulitis

*aureus, pyogenes

36
Q

Superficial cellulitis. S.pyogenes infx. Lymphatics. Dermis and above. FEVER. Face and legs

A

Erysipelas

37
Q

Only bacteria causing bullous impetigo

A

S. aureus

38
Q

Systemic bullous impetigo

A

(SSSS) Staphlococcal Scalded Skin Syndrome

39
Q

TSST-1

A

Toxic shock superantigen

40
Q

Strep causing toxic shock syndrome produce these exotoxins

A

M-1 and M-3

41
Q

Caused by a naked icosahedral dsDNA virus

A

Warts

*HPV

42
Q

Toxin related impetigo

A

Bullous

43
Q

Localized Impetigo

A

Bullous

44
Q

S. aureus serine proteases

A

Exfoliative toxins

-Epidermolytic toxin A and B

45
Q

Epidermolytic toxin A and B cleave

A

Desmoglein-1

46
Q

Phage type of S.aureus that cause Bullous Impetigo

A

Group II, Phage Type 71

47
Q

Two conditions caused by Epidermolytic toxin A and B

A

SSSS and Bullous Impetigo

48
Q

T/F: SSSS is just systemic spread of Toxin A and B

A

True

49
Q

S. aureus phage group causing SSSS

A

Group II, Phage Type 71