Saviola - Micro Flashcards
Produces CAMP factor and synergizes with S.aureus to increase hemolysis/cytolysis
P.acnes
Only POX virus to replicate in CYTOPLASM
Molluscom contagiosum
Pearly white hemispheric papule with depressed centers. HIV pts
Molluscum contagiosa
Double stranded DNA virus in ganglia
Varicella Zoster Virus
What is mode of spread of chickenpox in body?
Initially hematogenous spread (which is why it is systemic)
- Unicellular fungi.
- Reproduce via budding
- Smooth colonies on solid media (like bacteria)
- Pseudohyphae
Yeasts
- Multicellular
- Hyphae
- Filamentous colonies on media
Molds
mold in environment, yeast at body temp
medically important fungi
Superficial, cutaneous, or deep?
- Pityriasis Versicolor
- Tinea nigra
Superficial mycoses
What is Pityriasis tine versicolor caused by?
Malassezia furfur
What is Tinea nigra caused by?
Hortaea werneckii
Superficial lipophilic skin fungus condition
Pityriasis
*spaghetti and meatballs
Dermatophytes prefer which skin layer?
keratinized epidermis: skin, hair, nails
Monomorphic fungi that produce keratinases (to use keratin as food source). Cause immune response.
Cutaneous mycoses - dermatophytes
*Tinea capitis, cruris, manus, unguium, corporis
Dimorphic fungus with both yeast and mycelial forms
Candida albicans
*diaper rash
This one eats glucose and is a problem for diabetics and immune compromised
Candida albicans
- Dimorphic fungus
- Subcutaneous
- Accidental implantation
- Small ulcer–>nodule
- Lymphatic spread
Sporotrichosis
*Sporothrix schenckii
Subcutaneous
Sporotrichosis
2 bacteria that cause skin infections
Staph aureus
Strep pyogenes
Which skin infecting bacteria matches the following buzz words:
- clusters
- coagulase
- catalase positive
S. aureus
Which skin infecting bacteria matches the following buzz words:
- beta hemolytic
- bacitracin sensitive
- pairs and chains
S. pyogenes
*group A
Protein A
PVL (Panton-Valentine leukocidin)
S. aureus
M protein
S. pyogenes
- looks like our proteins, causing cross immune rxn,
- Strep is typed based on M protein
Increases pathogenicity of S. aureus
PVL
*creates pores in leukocytes = lysis
Name for superficial bacterial infection. Begins as pustule, progresses to vesicle, then crusts like dry honey
Impetigo
Impetigo is caused by
S. aureus or Group A Strep
Name for bacterial infection in dermis
Ecthyma
Ecthyma is caused by
Strep
Infected hair follicles are usually caused by _______, unless hot tub folliculitis which is caused by _______.
S. aureus
P. aeruginosa
An infection of many hair follicles
furunculosis
The bacteria causing furunculosis produce this VIRULENCE FACTOR
PVL
*Panton valentine leukocidin
Important for PATHOGENESIS of S. aureus because is helps form biofilm and aggregation
Protein A
*A for Aggregation
Non-bullous impetigo.
Biofilm with polysaccharide matrix
S. pyogenes
Microaerophilic bacteria causing inflammation in a cyst
Propionibacterium acnes
Acute, severe, rapid bacterial infection of DERMIS and deeper tissues. If systemic, causes fever, sweat, chills
Cellulitis
*aureus, pyogenes
Superficial cellulitis. S.pyogenes infx. Lymphatics. Dermis and above. FEVER. Face and legs
Erysipelas
Only bacteria causing bullous impetigo
S. aureus
Systemic bullous impetigo
(SSSS) Staphlococcal Scalded Skin Syndrome
TSST-1
Toxic shock superantigen
Strep causing toxic shock syndrome produce these exotoxins
M-1 and M-3
Caused by a naked icosahedral dsDNA virus
Warts
*HPV
Toxin related impetigo
Bullous
Localized Impetigo
Bullous
S. aureus serine proteases
Exfoliative toxins
-Epidermolytic toxin A and B
Epidermolytic toxin A and B cleave
Desmoglein-1
Phage type of S.aureus that cause Bullous Impetigo
Group II, Phage Type 71
Two conditions caused by Epidermolytic toxin A and B
SSSS and Bullous Impetigo
T/F: SSSS is just systemic spread of Toxin A and B
True
S. aureus phage group causing SSSS
Group II, Phage Type 71