Patel - Derm Infections Flashcards
A localized form of Staph Scalded Skin Syndrome
Bullous impetigo
Exfoliative toxin disturbs this epithelial adhesion protein
Desmoglein 1
The layer of skin that peels off with SSSS
Stratum granulosum
Temperature. Then in 1-2 days, skin wrinkles, then forms bullae (like sandpaper), then sloughs off in sheets.
Leftover skin is moist, red, glistening and tender.
SSSS
Sandpaper skin
Scarlet fever and SSSS
What’s different between Scarlet fever rash and SSSS rash?
Scarlet fever rash is NOT tender
- Systemic illness.
- Spread via TOXIN IN BLOOD
- Sheets of Sloughing Skin
Scalded Skin Syndrome
Is bacteria in blood culture with SSSS?
NO! Staph is local. The toxin is hematogenously spread.
ill-defined border
- erythema
- warmth
- pain, edema
- caused by staph or strep
Cellulitis
Purulent cellulitis is caused by
Staph
*The other one’s the other one
If left untreated, cellulitis can become
Cellulitis or bulls
Differential for cellulitis
DVT
Slide 14,15FIX Tx for outpatient non purulent cellulitis
Tx for group A strep
FIX Tx for outpatient purulent cellulitis
cover community acquired MRSA
FIX Tx for hospitalized cellulitis its
Cover MRSA and take culture if purulent
Causes Erysipelas
Group A Strep
Tx for Impetigo
Topical retapamulin or mupirocin twice daily for 1 week.
*oral antibiotics if needed
Complication from untreated or aggressive impetigo
Post-stretocococcal glomerulnephritis 1-5 wks post infection
Which type of Impetigo starts as bullae within stratum granulosum?
Bullous
Honey colored crust
Nonbullous Impetigo
Which type of Impetigo exhibits flaccid bullae with clear yellow fluid and no surrounding erythema?
Bullous Impetigo
Anti-DNAse B titer elevation
Group A strep Impetigo
Stratum corneum roof and exotoxins
S. aureus Impetigo
Most common cause of Impetigo
S. aureus
Cellulitis after body piercing usually caused by
S. aureus
*The others are Strep (IV drug, lipo, CABG, etc)
Tx for Erysipelas
Penicillin
This cellulitis is superficial, well demarcated, streaking, and caused by
Group A Strep (pyogenes)
*Erysipelas
Most common cause of Necrotizing fasciitis
Strep pyogenes
Causes necrotizing fasciitis in cirrhosis pts
Vibrio vulnificus
Causes necrotizing fasciitis and gas gangrene
Clostridium species
Causes peptostreptococcus necrotizing fasciitis
Anaerobic strep
Causes post herpetic neuralgia (PHN)
Varicella -Zoster Virus
This phase of Shingles is infective; live virus in the vesicles.
Eruptive Phase
Tx disseminated and ophthalmic zoster with
IV acyclovir