Aanderud - Vasculitis Flashcards
This size is the most common of the vasculitises
Small
Inflammation involving the respiratory tract and necrotizing vasculitis affecting small to medium-sized vessels; necrotizing glomerulonephritis is common.
Wegners Granulomatosis
*Granulomatosis with polyangiitis
C-ANCA positive
Wegners
P-ANCA positive
Churg-Strauss
Tx for Wegners Granulomatosis
Cyclophosphamide
Eosinophil-rich and granulomatous inflammation involving the respiratory tract, necrotizing vasculitis affecting small to medium sized vessels. Associated with asthma and eosinophilia
Churg-Strauss
Saddle nose deformities, and palpable purpura in mouth, tongue, nose (red nodules)
Wegners
*(with Polyangiitis)
Treat C-ANCA positive with what drug?
Cyclophosphamide
*C and C (Wegners)
Ridiculous amount of peripheral eosinophilia
Churg-Strauss
*(Eosinophilic Granulomatosis with polyangiitis)
IgA immune deposits surrounding blood vessels. Kids. Type 3 hypersensitivity rxn.
Henoch-Schonlein purpura
Kids’ vasculitis affecting small vessels. Usually involves skin, gut, glomeruli. Complaints = HA, joint pain, blood in urine, widespread red rash. IgA deposits
Henoch-Schonlein purpura
Purpura on extensor surfaces and buttocks
Henoch-Schonlein purpura
What test do you order if you suspect autoimmune dz like
ANA
What do you do if u suspect a vasculitis?
Get the biopsy, get the blood work, Tx with oral steroids, refer to derm
Name the hypersensitivity type:
-Anaphylactic
Type 1