Sarcoidosis Flashcards
to diagnosis sarcoidosis need
compatible clinical and radiological manifestations, exclusion of other diseases with similar presentation, histopathological evidence of non caseating granulomas
Differential for sarcoidosis if there’s mediastinal adenopathy
lymphoma, pulmonary infection, systemic disease (pneumoconiosis and vasculitis)
What is seen on biospy with sarcoidosis
non caseating granulomas.
What is Lofgren’s syndrome?
variant of sarcoidosis
see triad of hilar adenopathy, erythema nodosum (which can be described as violaceous) and acute polyarthritis
arthritis is seen in both ankles and other large joints of body
What do you need to do for Lofgren’s syndrome?
no tissue biopsy but need to get CXR or CT if XR is negative to identify hilar adenopathy
Treatment of lofgren’s syndrome
so normal and routine and self limiting that you only need to treat with NSAIDS
NO STEROIDS
Who get’s Lofgren’s syndrome?
Africans, scandinavians, Irish, and puerto ricans.
Is lofgren’s related to SLE or RA?
no it’s related to sarcoidosis.
Eye complication of sarcoidosis
uveitis
where do we see arthritis related to sarcoidosis?
ankle and knee joints and don’t really see enthesitis or inflammatory back pain.
pulmonary sarcoidosis staging: stage I
bilateral hilar adenopathy and often right paratracheal node enlargement
hilar adenopathy
pulmonary sarcoidosis staging: stage 2
bilateral hilar adenopathy and reticular opacities (upper>lower lobes)
reticular opacities
pulmonary sarcoidosis staging: stage 3
reticular opacities (upper lobes mostly) and shrinking hilar nodes
pulmonary sarcoidosis staging: stage 4
reticular opacities + volume loss (mostly upper lobes)
most common skin manifestation of sarcoidosis
erythema nodosum-panniculitis
