antibodies to Rheum conditions Flashcards by Christine Hsu | Brainscape

Q

drug induced SLE

A

DNA histone complex (95%)

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Q

SLE

A

ds DNA, Smith

positive ANA

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Q

systemic sclerosis (scleroderma)

A

Can have positive ANA antibody

RNA polymerase II and III
Scl 70/anti topoisomerase I

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Q

Mixed connective tissue dx

A

RNP (100%)

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Q

Sjogren’s syndrome:

A

SS-A/Ro, SS-B/La

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Q

Limited scleroderma

A

anti Centromere - think CREST

can have positive ANA

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Q

Polymyositis, dermatomyositis

A

Aminoacyl-tRNA, synthetases (Jo-A)

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Q

Microscopic polyangiitis

A

myeloperoxidase (MPO)

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Q

Granulomatosis with polyangiitis (Wegener’s)

A

proteinase 3 (PR3)

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Q

primary biliary cirrhosis:

A

anti- mitochondrial antibodies

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Q

autoimmune hepatitis

A

anti smooth muscle antibodies

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Q

primary biliary cholangitis

A

seen with UC

ANCA positive

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