Sarcoidosis Flashcards

1
Q

What skin signs?

A

Erythema Nodosum

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2
Q

What ethnicity?

A

Black

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3
Q

What chest signs?

A

Mediastinal lymphadenopathy
Pulmonary fibrosis
Pulmonary nodules

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4
Q

How does heart change?

A

BBB

Heart block

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5
Q

Eye signs in sarcoidosis?

A

Optic neuritis
Uveitis
Conjuctivitis

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6
Q

Liver sarcoidosis

A

Liver nodules
Cirrhosis
Cholestasis

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7
Q

Neurological sarcoidosis

A
Facial nerve palsy
Mononeuritis multiplex
Nodules
Pituitary involvement (diabetes insipidus)
Encephalopathy
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8
Q

Kidney sarcoidosis

A

Kidney stones (due to hypercalcaemia)
Nephrocalcinosis
Interstitial nephritis

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9
Q

Systemic symptoms of sarcoidosis

A

Fatigue
Weight loss
Fever

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10
Q

What Ix for sarcoidosis

A

U&Es for kidney involvement
Urine dipstick or urine albumin-creatinine ratio to look for proteinuria indicating nephritis
LFTs for liver involvement
Ophthalmology review for eye involvement
ECG and echocardiogram for heart involvement
Ultrasound abdomen for liver and kidney involvement

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11
Q

How to manage sarcoidosis

A

No treatment is first line
Oral steroids for between 6 and 24 months. Bisphosphonates
Second line options are methotrexate or azathioprine
Lung transplant is rarely required in severe pulmonary disease

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12
Q

What is prognosis

A

Sarcoidosis spontaneously resolves within 6 months in around 60% of patients.
Small proportion lung transplant.
Death in sarcoidosis is usually when it affects the heart (causing arrhythmias) or the central nervous system.

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