Interstitial Lung Disease Flashcards
How is interstitial lung disease diagnosed?
High res CT- ground glass
Biopsy
What is generalised management of Interstitial lung disease?
Remove cause Home O2 when needed Stop smoking Physio and pulmonary rehab Pneumococcal and flu vaccines Advanced care planning
What is IPF?
Idiopathic Pulmonary fibrosis
Progressive fibrosis with no clear cause
Presents wih SOB and cough for 3 months
What is seen on examination with IPF?
Finger clubbing
Bibasal crackles
What slows IPF progression?
Pirfenidine (anti inflammatory)
Nintedanib (monoclonal ab)
Which drugs cause drug induced lung fibrosis?
Amiodarone
Cyclophosphamide
Methotrexate
Nitrofurantoin
What can pulmonary fibrosis occur secondary to?
A1ATD
RA
SLE
SS
What is hypersensitivity Pneumonitis?
Type 3 hypersensitivity
Parenchymal inflammation in those sensitive to allergen
Bronchoalveolar lavage shows raised lymphocytes an dmast cells
How is hypersensitivity pneumonitis managed?
Remove cause
Oxygen
Steroids
What are specific causes of hypersensitivity pneumonitis?
Bird fanciers lung
Farmers lung
Malt workers lung
Why would you test serum ACE?
Sarcoid
How would you test for Wegeners?
ANCA
What causes lesions in the upper lobe on CT?
Sarcoid, EAA, Silicosis
WHat causes lesions in the lower lobe on CT?
IPF, DIP, Asbestososis
What causes central lesions on CT?
Sarcoid
