Salivary secretion

Question 1

Describe

• Sympathetic
• Parasympathetic regulation of salivary secretions
• Environmental stimuli

Answer 1

Sympathetic
-via sup cervical ganglia => amylase

Parasympathetic

• via X => acing saliva, ductal HCO3 secretion
• via NANC => increased blood flow, my-epithelium contraction

Environmental

• Taste/chewing, hot/cold, pain, smell stimulate salivation
• Sleep, fear, fever, depression inhibits salivation

Question 2

3 main functions of saliva

Answer 2

Digestion

• amylase, lipase
• swallowing

Protection
-buffering, antimicrobicidal (increased IgA secretion)

Speech

Question 3

Describe the route of saliva

Answer 3

Increased blood flow to sustain active secretion (many NaKATPase)

Acinar cells => isotonic primary saliva

Duct cells => hypotonic K, HCO3 rich secondary section

Question 4

Causes of hypo salivation

Answer 4

Gland atrophy due to age

Salivary gland hypofunction

Question 5

Name the 3 salivary glands and their functions

Answer 5

Parotid => serous, watery, enzymes

Sublingual => mucus, thick

Submandibular => mixture of serous and mucus