Salivary Glands Flashcards
From what tissue layer are salivary glands derived?
Ectoderm
What are the 5 stages of salivary gland development?
1-Prebud 2-Initial bud 3-Psuedoglandular 4-Canalicular 5-Terminal bud
What tissue is responsible for the branching of salivary glands?
Salivary mesenchyme
*interacts with salivary epithelium to create the salivary gland
During the canalicular stage, what process must take place in surrounding tissues to make room for the lumen?
Caspase mediated apoptosis
Salivary gland development depends on what two neurotransmitters?
1-Acetylcholine (parasympathetic from otic ganglion at the time of gland formation)
2-Norepinephrine (sympathetic from efferent nerves in the cervical ganglion)
What stages go wrong when aplasia of lacrimal and salivary glands results?
Pre-bud to initial bud
Which stages go wrong when lacrimoauriculodentodigital syndrome happens?
Initial bud to pseudoglandular
Which stage goes wrong to result in hizohidrotic ectodermal displasia?
Canalicular stage
What are the 3 major salivary glands through which 90% of saliva is made?
1-Parotid gland (mainly serous)
2-Submandibular gland (mixed serous and mucous)
3-Sublingual gland (mainly mucous)
The outside of an acinus is called?
Basolateral
*Inside is apical
Which cells stain lighter and has flat nuclei?
Mucous cells
Which cells secrete watery saliva?
Serous cells
Where are stem cells and progenitor cells found?
Intercalated duct
Where is saliva modified?
Striated duct
Which neurotransmitter is associated with the parasympathetic nervous system, M3R receptor, Gq protein, Phospholipase C, and IP3?
Acetylcholine
*water and fluid secretions
