Salivary Glands Flashcards
E/O checks for salivation issues
Palpate parotid and submandibular
I/O checks for salivation issues (4)
Duct orifices
Minor salivary glands
Fluid expression
Quality of saliva
Functions of saliva (4)
Acid buffering (neutralises)
Lubrication for speech + swallowing
Taste
Antibacterial
List some causes of a dry mouth (5)
Medications - Ca channel blockers, antihypertensives
Dehydration
Salivary gland disease
Somatisation disorders + anxiety
Radiotherapy/chemotherapy
List medical conditions that induce saliva reduction indirectly (5)
Diabetes
Stroke
Addisons disease
VBD
List medical conditions that induce saliva reduction directly (problems with gland itself) (5)
Aplasia - ectodermal dysplasia
Sarcoidosis
HIV
Gland infiltration - amyloidosis
CF
What part of body affected by ectodermal dysplasia? (5)
Hair
Nails
Teeth
Sweat glands
Salivary glands
Hearing + vision
Name a scale used to measure mucosal dryness
Challacombe scale of mucosal dryness
Investigations for Salivary disease (5)
- Blood tests
FBCS
U+Es
LFT
C reactive protein
Glucose
Anti-Ro antibody
Anti-la antibody - Functional assays - salivary flow
- Tissue assays - labial gland biopsy
- Imaging
- Plain radiographs
- Sialography
- Ultrasound
Function of sialography
Contrast to show ducts
Disadvantage of sialography
Ionising radiation
Risk of labial gland biopsy
Lip numbness
How does anxiety reduce saliva flow?
Inhibits salivary production by brain
What is a somatoform disease?
Mental health condition
Cause physical body symptoms in response to psychological stress
Examples of somatoform disease
IBS
TMD
Oral dysaesthesia
Unstimulated saliva flow
<1.5ml in 15 mins = hypo salivation
Untx causes of dry mouth
- Sjogrens
- From cancer tx
- From salivary gland disease
Dry eye test for dry mouth
Schirmer test tear flow <5mm in 15mins
Examples of salivary substitutes
Sprays
Glandosane (acidic)
Orthana (encouraged)
Stimulants
Pilocarpine (sweating/taccychardia)
Medical condition causes of hyper-salivation
Dementia
Stroke
Anxiety
Cerebral palsy
Medications that can cause hyper-salivation (3)
Clozapine
Ketamine
Bromides
Treating hyper salivation
Botox
Anxiety - tx
Antimuscarinic agents
List some reasons for changes in gland size
Viral infection - herpes/mumps
Secretion retention - mucoceles/obstruction
Gland hyperplasia
Salivary neoplasms
Sialadenitis - infection
Symptoms of mumps (6)
- High temp
- Nausea
- Loss of appetite
- Abdominal pain
- Headache
- Joint pain
Common feature of duct obstruction
Swelling increases with meals
Usually submandibular as ductal pathway longer
Investigations for duct obstruction
Low dose plain radiograph
Lower true occlusal - submandibular
Ultrasound
Cause of duct obstruction
Sialolith
Mucous plugging
Duct stricture - due to infection/damaged duct
Histopathology of non specific sialadentitis
Fibrous scar tissue
Management of subacute obstruction
Surgical sialolith removal
Sialography for no stone cases - dye to wash mucous plug away
Define sialolis
Chronic painless swelling of major salivary gland - usually parotid
Define Sjogrens Syndrome
Autoimmune disease that causes loss of salivary/lacrimal tissue through T lymphocytic inflammatory destruction
Classifications of Sjogrens
Partial
- Sicca syndrome
- Dry eyes or mouth
Primary
- No connective tissue disease
Secondary
- Connective tissue disease
Systemic diseases Sjogrens is linked to
RA
Lupus
Scleroderma
Consequences of Sjogrens
- 5% malignancy risk of lymphoma
- Inc caries/oral infection/functional issues - speech+ swallow
- Enlargement of salivary glands
Immunopathology findings of Sjogrens
Lymphocytic focci within salivary tissue from labial gland biopsy
Sialography findings of Sjogrens
Snow storm
Leopard spots
What is used to help confirm diagnosis of Sjogrens?
AECG
Oral symptoms of sjogrens
Dry mouth >3mths
Swelling of salivary glands
Ocular symptoms of sjogrens
Dry eyes >3mths
Sand/gravel in eyes
Eye drops >3x a day
Criteria of AECG required
- Dry eyes/mouth
- Histopathology - focci present
- AntiRo/La
- Ultrasound
Management of Sjogrens
OHI
Spray/stimulant
If present early lease with rheumatologist and consider immune modulating drug Hydroxychloroquine