Salivary gland disease Flashcards

1
Q

What serious disease can achalasia lead to?

A

Squamous cell carcinoma

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2
Q

What kind of enzyme is Pepsin?

A

Enteropeptidase

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3
Q

What is important about the cephalic phase of gastric secretion?

A

Completely vagal mediated

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4
Q

What are the infectious etiologies of sialadenitis?

A

Mumps
S. aureus
Fungal

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5
Q

What are some non-infectious etiologies of sialadenitis?

A

Sjogrens
Sarcoidosis
Radiation

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6
Q

Swollen/painful parotid gland with purulent discharge from the parotid duct is most likely?

A

Acute bacterial sialadenitis

Play odds: S. aureus

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7
Q

Chronic pain and swelling of salivary gland at mealtime?

A

Sialolith or other obstruction

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8
Q

Kuttner tumor?

A

Persistent enlargement of the submandibular gland

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9
Q

Most common benign salivary gland?

A

Pleomorphic adenoma

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10
Q

Benign salivary tumor with ductal and myoepithelial elements?

A

Pleomorphic adenoma

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11
Q

What is the Tx for pleomorphic adenoma?

A

surgical excision

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12
Q

What is the 2nd most common benign salivary tumor?

A

Papillary cystadenoma lymphomatosum (Warthin’s tumor)

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13
Q

60 yo male with parotid mass that show cystic spaces with double cell layer in a prominent lymphoid stroma?

A

Papillary cystadenoma lymphomatosum (Warthin’s tumor)

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14
Q

What is the most common malignant tumor of salivary tissue?

A

mucoepidermoid carcinoma

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15
Q

Most common location for mucoepidermoid carcinoma?

A

Parotid gland

minor palate glands

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16
Q

What is the pathophysiology of mucoepidermoid carcinomas?

A

MECT1-MAML3 fusion protein –> alters cAMP signaling.

17
Q

What is the best indicator of prognosis in mucoepidermoid carcinoma?

A

Grade (which is unusual b/c stage is usually better)

18
Q

Sheets of mucus, squamous, and intermediate cells?

A

mucoepidermoid carcinoma