Salivary Gland Flashcards
Parotid glands secretly mostly?
Serous saliva
Parotid glands are supplied by
Parasympathetic fibers from IX
Which is the largest salivary gland?
Parotid
What is the relation of the parotid gland?
Posterior aspect of masseter muscle, below ear
Wraps around posterior border of mandible
Superficial and deep lobe is divided by facial nerve
What are the relations of the parotid duct?
Lies on masseter
At anterior border of mandible, duct turns medially, pierce buccinator muscle and opens adjacent to maxillary 2nd molar
Where is the submandibular duct located?
Submandibular triangle of neck
Partly superficial and deep to mylohyoid muscle
Path of submandibular (wharton’s) duct?
Opens floor of mouth at punctum lateral to lingual frenum
What is the relation of lingual nerve to submandibular duct?
Lingual nerve loops under Wharton’s duct from lateral to medial in the posterior mouth
Location of sublingual duct?
Lies on superior surface of mylohyoid muscle
Path of sublingual duct
Open into floor of mouth or submandibular duct
What innervates sublingual and submandibular glands
VII through the chorda tympani nerve
Sublingual gland produces
Mucous saliva
Minor salivary glands produce
Mucous saliva?
What are the radiographs taken for salivary glands?
- Plain films: True occlusal mandible
- Sialography
- CT scans
- MRI
What bacteria causes sialdenitis?
Staphylococcus aureus
What is Mumps?
Acute infection caused by paramyxovirus
What age is Mumps common in?
3-8 years old
What are the symptoms of Mumps?
Painful swelling of one or both parotid and submandibular glands
Fever, chill, headaches
Symptoms 16-18 days after exposure and last 5-12 days
Vaccination of MMR should be given at what age?
Infancy
Treatment of Mumps
- Symptomatic care
- Analgesics, anti-pyretics, hydration
How did bacteria infection of salivary duct arise?
Blocked ducts or decreased salivary flow
Treatment of Acute Bacterial Sialadenitis
- Symptomatic and supportive care: IV fluid hydration
- Culture and sensitivity of causative organism
- Antibiotics, analgesics
List Obstructive Salivary Gland Disease
- Sialolithiasis
- Mucocele
- Ranula
What is sialolithiasis?
Calcified structures that develop within ductal system that arise from deposition of calcium salts around a nidus of debris
Which gland is Sialolithiasis more common in?
Submandibular gland
What can Sialolithiasis cause?
- Recurrent sialadenitis
- Bigger stones can cause episodic pain in affected gland, meal-time symptoms
Management of sialolithiasis?
Surgical removal of salivary stone
What is sialoendoscopy?
Endoscopic transluminal of ductal system of major salivary glands which can remove stones up to 4mm diameter
Bigger stones can be fragmented with Holmiun laser
Ranula is often a?
Mucous retetion cyst
Mucocele is often a?
Mucous extravasation cyst
Treatment of Ranula
Marsupialisation
Characteristics of Salivary Gland Neoplasms
- Swelling that is increasing in size
- Painless, sometimes dull ache
- Firm to rubbery in texture
What is the most common of all salivary gland neoplasms
Pleomorphic adenoma
Treatment of Pleomorphic Adenoma
Complete surgical excision of lump and gland
Avoid enucleation and tumour spill
What is the histology of Pleomorphic Adenoma?
- Mixture of epithelial, myoepithelial and stromal components
- No true capsule
Clinical signs of Warthin Tumour?
Slow growing, painless, usually appears in the tail of the parotid gland
What is the predisposing factor for Warthin’s tumour?
Smoking
What is the most common salivary gland malignancy?
Mucoepidermoid Carcinoma
Which salivary gland is Mucoepidermoid Carcinoma most common in?
Parotid gland
What age is Mucoepidermoid Carcinoma common in?
30-80 years old, peak in 50 years old
Clinical sign of Mucoepidermoid Carcinoma
Low grade: Slow-growing painless mass
High grade: Rapidly enlarging with or without pain
- Well-circumscribed to partially encapsulated/unencapsulated
- Solid tumour with cystic spaces
What is the histology for low-grade Mucoepidermoid Carcinoma?
- Mucus cells > Epidermoid cells
- Prominent cysts
- Mature cellular elements
What is the histology for intermediate-grade Mucoepidermoid Carcinoma?
- Mucus=Epidermoid cells
- Fewer and smaller cysts
- Increasing pleomorphism and mitotic figures
What is the histology for high-grade Mucoepidermoid Carcinoma
- Epidermoid> Mucus cells
- Solid tumour cell proliferation
- Mistaken for SCC
What is the treatment for Mucoepidermoid Carcinoma?
Influenced by site, stage,grade
Stage I and II: Wide local excision
Stage III and IV: Radical excision +/- Neck dissection +/- Postoperative radiation therapy
What is the 2nd most common salivary gland malignancy?
Adenoid cystic carcinoma
Which salivary gland is Adenoid Cystic Carcinoma most common in?
50% Parotid 50% Minor Salivary Glands
Which age is Adenoid Cystic Carcinoma most common in?
50 years old
Clinical signs of Adenoid Cystic Carcinoma
- Slow-growing enlarging mass
- Dull pain paraesthesias, facial weakness/paralysis
- Perineural invasion
What is the histology of Adenoid Cystic Carcinoma?
Infiltrative proliferation of basaloid cells arranged in cribriform pattern
What is the treatment of Adenoid Cystic Carcinoma?
Complete local excision + Facial nerve sacrifice + Postoperative radiotherapy
Prognosis of Adenoid Cystic Carcinoma
Local recurrence 42%
Distant metastasis to the lung
5 year survival rate 75%
20 year survival rate 13%