Salicylazosulfapyrine (Azulfidine)

Question 1

Salicylazosulfapyrine (Azulfidine): Class

Answer 1

• GI Agent
• Salicylate (aspirin)

Question 2

Salicylazosulfapyrine (Azulfidine) is used to treat…

Answer 2

• Rheumatoid Arthritis
• Inflammatory Bowel Disease
  
  • Crohn’s disease
  • Ulcerative Colitis

Question 3

How does Salicylazosulfapyrine (Azulfidine) work?

Answer 3

Decreases GI inflammation through direct contact with bowel mucosa

Question 4

The patient on Salicylazosulfapyrine (Azulfidine) needs periodic testing for _____ and ____ via what lab(s)?

Answer 4

• Hepatitis and bone marrow suppression
• CBC/platelet count

Question 5

True or False

Salicylazosulfapyrine (Azulfidine) should be taken before meals to decrease the risk of GI upset

Answer 5

False, it should be taken WITH food

Question 6

Why should a patient on Salicylazosulfapyrine (Azulfidine) make sure to stay hydrated with > 2500mL/day of fluids?

Answer 6

To prevent crystallization

Question 7

While taking Salicylazosulfapyrine (Azulfidine), the patient needs to be on what supplement? Why?

Answer 7

• Folic acid
• Taking Aulfidine reduces folic acid levels.
• Folic acid supplements will need to be taken to keep them at normal levels

Question 8

Salicylazosulfapyrine (Azulfidine): SFX

Answer 8

• Hepatitis
• Bone marrow suppressioin
• Abdominal pain
• Rash (hives)
• Arthraglia (joint pain)
• Yellow/Orange skin/urine
• Increased photosensitivity
• Renal Failure