Lactulose (Duphalac) Flashcards
Lactulose (Duphalac) is given to the pt with…
- Cirrhosis
- Chronic constipation
How does Lactulose (Duphalac) treat constipation?
- It is poorly absorbed in the small intestine and colon and cannot be digested by intestinal enzymes.
- The osmotic action retains water, thereby softening feces
- Fecal swelling then promotes peristalsis (1-3 days)
How is Lactulose (Duphalac) administered?
Via liquid or enema
Lactulose (Duphalac) will reduce serum _____ levels.
Ammonia
Lactulose (Duphalac) tx is deemed effective if a patient has…
2-3 stools a day
Lactulose (Duphalac) is only used for pts that don’t respond to…
Other (bulk-forming) laxatives
Why is Lactulose (Duphalac) given to pts with portal hypertension and/or hepatic encephalopathy secondary to chronic liver disease?
Because it lowers serum ammonia levels
Why do we teach a pt taking Lactulose (Duphalac) to check for watery stools?
It may indicate toxic levels of the medication
Lactulose (Duphalac): SFX?
- Cramping/Intestinal bloating
- Flatulence
- Watery stools/Dehydration
- Hypokalemia
- Hypernatremia