Metoclopramide (Reglan)

Question 1

What is Metoclopramide (Reglan) used to treat?

Answer 1

GERD

Question 2

Metoclopramide (Reglan): Class?

Answer 2

Antiemetic (prokenietic)

Question 3

Metoclopramide (Reglan): Mode of Action?

Answer 3

• Acts as a prokinetic agent to promote gastric emptying (reducing the risk of gastric acid reflux).

Question 4

Metoclopramide (Reglan) is contraindicated for patients with…

Answer 4

• Parkinson’s
• GI obstruction
• Hx of seizures

Question 5

Use of Metoclopramide (Reglan) is used as a last resort when…

Answer 5

Other methods of conventional therapy aren’t working

Question 6

Metoclopramide (Reglan): SFX?

Answer 6

• Tardive Dyskinesia (involuntary movement of the face, eyes, limbs, or muscle rigidity)

Question 7

Metoclopramide (Reglan): Administration?

Answer 7

• Mix oral solution with water, juice or carbonated beverage
• Take 30 minutes before eating

Question 8

What type of drugs stop the effect of Metoclopramide (Reglan)?

Answer 8

• Antidepressants
• Antihistamines
• Opioids

Question 9

What drugs does Metoclopramide (Reglan) decrease the blood levels of?

Answer 9

• Cemetadine
• Digoxin

Question 10

Metoclopramide (Reglan) increases the risk of extrapyramidal reactions of what two other drugs?

Answer 10

• Haloperidol
• Phenothiazides

Question 11

What drug decreases Metoclopramide (Reglan) efficacy?

Answer 11

Levodopa

Question 12

A pt taking Metoclopramide (Reglan) should report…

Answer 12

• Involuntary movement of the face, eyes, limbs, or muscle rigidity
• Altered consciousness
• Irregular pulse or heartbeat