Salbutamol Flashcards
What is salbutamol?
Salbutamol (5mg NEB) is a direct acting sympathomimetic agent which mainly affects B2 adrenoreceptors. It primarily acts as a bronchodilator but also has inotropic and chronotropic actions. It also lowers serum potassium level through its direct stimulation of the sodium/potassium ATPase pump, drawing potassium into cells.
Hepatic metabolism with renal excretion.
Onset: 2-5 min
Duration: 16-60 min
Half-life: 1.6 hrs
Indications for salbutamol?
- Bronchospasm
2. (CCP) Suspected hyperkalaemia (with QRS widening and/or AV dissociation)
Contraindications for salbutamol?
- Allergy/ADR
2. Patients under 1 year
Precautions for salbutamol?
- Acute pulmonary oedema
2. Ischaemic heart disease
Side effects of salbutamol?
- Anxiety
- Tachyarrhythmias
- Tremors
- Hypokalaemia & metabolic acidosis
What is the dose of salbutamol for an adult?
5 mg NEB
Repeated PRN
No max dose
What is the dose of salbutamol for a paediatric?
1-5 years
2.5mg NEB
Repeated PRN
No max dose
5-12 years
5mg NEB
Repeated PRN
No max dose