S7 L1 - Adaptive immune response - Effector phase Flashcards

Question 1

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Plan of this lecture

Answer

A

B and T lymphocytes (Background/overview including: Where produced, accumulation of them, lymphadenopathy)

*T lymphocytes:**
How T lymphocytes recognise the antigen presented to it (structure of TCR complex)
Activation of T lymphocytes (3 signals needed) Same for CD4+ and CD8+ cells
Activation of CD4+ T cells (T helper cells)
Activation of CD8+ T cells (Effector function) and their role
*B lymphocytes:**
How do B cells recognise antigens (structure of BCR - B cell receptor)
How B lymphocytes are activated (multiple signals needed)
Outcome of B lymphocyte activation
*More about Antibodies:**
Antibody heavy chain class (isotype) switching
Characteristics of the antibody response
Effector function of Antibodies
*Summary:**
How to explain the clinical signs of inflammation
Medical achievements derived from the study of the adaptive immune response
Overview of intracellular repsonse leading to…, extracellular response leading to…

Question 2

Q

*B and T lymphocytes (Background/overview including): (1/1)
**Where produced?
Where do they accumulate?
Sign of infection - linked to lymphocytes

Question 3

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T lymphocytes: (1/4)
How T lymphocytes recognise the antigen presented to it (structure of TCR complex)?
- TCR complex
- Diversity of antigen receptor
- Forms of antigen recognised
- Different subunits

Question 4

Q

T lymphocytes (2/4)
Activation of T lymphocytes (3 signals needed) *Same for CD4+ and CD8+ cells*
- Three signals

Question 5

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T lymphocytes (3/4)
Activation of CD4+ T cells (T helper cells)
- 4 types of T helper cells and their roles

Question 6

Q

T lymphocytes (4/4)
Activation of CD8+ T cells (Effector function) and their role

Question 7

Q

B lymphocytes: (1/3)
How do B cells recognise antigens (structure of BCR - B cell receptor)
- Antigen recognition receptor structure
- Diversity of antigen receptors
- Forms of antigen recognised