RR Contraindications

Question 1

PDE-5 inhibitors

Answer 1

Alfuzosin, doxazosin,
tamsulosin, and
terazosin

Question 2

potent inhibitors of
P450 enzymes (e.g., ketoconazole)

Answer 2

Alfuzosin, doxazosin,
tamsulosin, and
terazosin

Question 3

calcium channel blockers (diltiazem and

verapamil)

Answer 3

Dutasteride

Question 4

anticoagulants or 2. hormone therapy

Answer 4

Saw palmetto

Question 5

oral
contraceptive and hormone replacement
therapy

Answer 5

Saw palmetto

Question 6

Severe hepatic impairment

Answer 6

Antiandrogens
Bicalutamide &
flutamide
Nilutamide

Question 7

respiratory insufficiency

Answer 7

Nilutamide

Question 8

methotrexate, 6-
mercaptopurine, and azathioprine–> bone
marrow suppression

Answer 8

Trimethoprim-

Sulfamethoxazole

Question 9

Bacteriostatic agents (e.g., TCN)

Answer 9

Penicillins

Ceftriaxone

Question 10

pregnancy; may cause hemolytic anemia in neonate

Answer 10

Nitrofurantoin

Question 11

Sulfonamide allergies

Answer 11

TMP-SMX
Dorzolamide; acetazolamide
FUROSEMIDE
Thiazide diuretics

Question 12

COPD

Answer 12

CA inhibitors; dorzolamide; acetazolamide

Propranolol

Question 13

Pulmonary congestion

Answer 13

Mannitol

Question 14

Heart failure

Answer 14

Mannitol

Question 15

Severe renal disease

Answer 15

Mannitol

Question 16

Aminoglycosides (ototoxicity

Answer 16

Loop diuretics

Question 17

NSAIDs (decreases efficacy)

Answer 17

Loop diuretics

Thiazide diuretics

Question 18

Oral hypoglycemics (efficacy decreased)

Answer 18

Loop diuretics

Thiazide diretics

Question 19

Anuria

Answer 19

Thiazide diuretics

K sparing diuretics

Question 20

other potassiumsparing

diuretics, potassium supplements

Answer 20

K sparing diuretics

Question 21

Angiotensin Receptor Blockers (losartan etc)

Answer 21

K sparing diuretics

Question 22

ACEIs (hyperkalemia)

Answer 22

K sparing diuretics

Question 23

antacids

Answer 23

Ferrous sulfate and

ferric gluconate

Question 24

proton-pump inhibitors

Answer 24

Ferrous sulfate and

ferric gluconate

Question 25

Interferes with absorption of other drugs | including oral iron

Answer 25

Calcium acetate & | calcium carbonat

Question 26

Oral iron

Answer 26

Calcium acetate & | calcium carbonat

Question 27

Cholestyramine (reduces absorption)

Answer 27

Calcitriol, paricalcitol

Question 28

Nitrates (severe hypotension)

Answer 28

Sildenafil, tadalafil, | vardenafil

Question 29

pts at risk of ophthalmologic problems

Answer 29

Sildenafil, tadalafil, | vardenafil

Question 30

airplane pilots

Answer 30

Sildenafil, tadalafil, | vardenafil

Question 31

Sickle cell disease (risk of priapism) Lymphoproliferative disorders (risk of priapism)

Answer 31

Alprostadil

Question 32

Thrombocytopenia

Answer 32

Alprostadil

Question 33

Anticoagulants

Answer 33

Alprostadil | Saw Palmetto

Question 34

Prostate cancer | BPH

Answer 34

Testosterone | replacement

Question 35

asthma patients

Answer 35

Propranolol

Question 36

Verapamil and Diltiazem

Answer 36

Dutasteride

Question 37

Pregnancy

Answer 37

ACE inhibitors;ARBs; Alisikren TMP-SMX Floroquinolones Nitrofurantoin Finasteride/Dutasteride

Question 38

Take with FOOD

Answer 38

cinacalcet

Question 39

Take without food

Answer 39

Penicillins; | Ferrous sulfat and Ferric gluconate