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Renal Pharm > RR Contraindications > Flashcards

RR Contraindications Flashcards

1
Q

PDE-5 inhibitors

A

Alfuzosin, doxazosin,
tamsulosin, and
terazosin

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2
Q 
potent inhibitors of
P450 enzymes (e.g., ketoconazole)
A

Alfuzosin, doxazosin,
tamsulosin, and
terazosin

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3
Q

calcium channel blockers (diltiazem and

verapamil)

A

Dutasteride

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4
Q

anticoagulants or 2. hormone therapy

A

Saw palmetto

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5
Q

oral
contraceptive and hormone replacement
therapy

A

Saw palmetto

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6
Q

Severe hepatic impairment

A

Antiandrogens
Bicalutamide &
flutamide
Nilutamide

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7
Q

respiratory insufficiency

A

Nilutamide

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8
Q

methotrexate, 6-
mercaptopurine, and azathioprine–> bone
marrow suppression

A

Trimethoprim-

Sulfamethoxazole

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9
Q

Bacteriostatic agents (e.g., TCN)

A

Penicillins

Ceftriaxone

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10
Q

pregnancy; may cause hemolytic anemia in neonate

A

Nitrofurantoin

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11
Q

Sulfonamide allergies

A

TMP-SMX
Dorzolamide; acetazolamide
FUROSEMIDE
Thiazide diuretics

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12
Q

COPD

A

CA inhibitors; dorzolamide; acetazolamide

Propranolol

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13
Q

Pulmonary congestion

A

Mannitol

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14
Q

Heart failure

A

Mannitol

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15
Q

Severe renal disease

A

Mannitol

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16
Q

Aminoglycosides (ototoxicity

A

Loop diuretics

17
Q

NSAIDs (decreases efficacy)

A

Loop diuretics

Thiazide diuretics

18
Q

Oral hypoglycemics (efficacy decreased)

A

Loop diuretics

Thiazide diretics

19
Q

Anuria

A

Thiazide diuretics

K sparing diuretics

20
Q

other potassiumsparing

diuretics, potassium supplements

A

K sparing diuretics

21
Q

Angiotensin Receptor Blockers (losartan etc)

A

K sparing diuretics

22
Q

ACEIs (hyperkalemia)

A

K sparing diuretics

23
Q

antacids

A

Ferrous sulfate and

ferric gluconate

24
Q

proton-pump inhibitors

A

Ferrous sulfate and

ferric gluconate

25
Q

Interferes with absorption of other drugs

including oral iron

A

Calcium acetate &

calcium carbonat

26
Q

Oral iron

A

Calcium acetate &

calcium carbonat

27
Q

Cholestyramine (reduces absorption)

A

Calcitriol, paricalcitol

28
Q

Nitrates (severe hypotension)

A

Sildenafil, tadalafil,

vardenafil

29
Q

pts at risk of ophthalmologic problems

A

Sildenafil, tadalafil,

vardenafil

30
Q

airplane pilots

A

Sildenafil, tadalafil,

vardenafil

31
Q

Sickle cell disease (risk of priapism)
Lymphoproliferative disorders (risk of
priapism)

A

Alprostadil

32
Q

Thrombocytopenia

A

Alprostadil

33
Q

Anticoagulants

A

Alprostadil

Saw Palmetto

34
Q

Prostate cancer

BPH

A

Testosterone

replacement

35
Q

asthma patients

A

Propranolol

36
Q

Verapamil and Diltiazem

A

Dutasteride

37
Q

Pregnancy

A

ACE inhibitors;ARBs; Alisikren

TMP-SMX
Floroquinolones
Nitrofurantoin

Finasteride/Dutasteride

38
Q

Take with FOOD

A

cinacalcet

39
Q

Take without food

A

Penicillins;

Ferrous sulfat and Ferric gluconate

Renal Pharm (14 decks)

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