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Renal Pharm > Clinical Uses > Flashcards

Clinical Uses Flashcards

1
Q

Complicated pyelonephritis

A

penicillins ceftriaxone aminoglycosides

fluoroquinolones

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2
Q

Primarily to treat severe or intractable hypertension

A

Minoxidil; Pinacidil

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3
Q

Pulmonary and peripheral edema Edema associated with hypoalbuminemia (caused by liver disease or nephrotic proteinuria) Hypercalcemia (caused by malignancy or hyperparathyroidism) Hyperkalemia (caused by potassium-retaining drugs or renal insufficiency) Hyponatremia

A

Ethacrynic acid

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4
Q

Preferred in hypertensive diabetic patients (delay the onset/progression of diabetic renal damage)

A

Captopril, Lisinopril, Enalapril, Ramipril

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5
Q

i. Acute mountain sickness ii. Restore acid-base balance in heart failure patients with metabolic alkalosis caused by loop diuretics

A

Acetazolamide

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6
Q

Candidiasis pyelonephritis

A

Azoles (fluconazole)

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7
Q

Reduces formation of aqueous humor and thus lowers intraocular pressure in treating open angle glaucoma

A

Dorzolamide

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8
Q

First line for ED

A

Sildenafil, tadalafil, vardenafil

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9
Q

Used mainly in men with hypertension plus BPH

A

Prazosin; Doxazosin

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10
Q

Pulmonary and peripheral edema Edema associated with hypoalbuminemia (caused by liver disease or nephrotic proteinuria) Hypercalcemia (caused by malignancy or hyperparathyroidism) Hyperkalemia (caused by potassium-retaining drugs or renal insufficiency) Hyponatremia HTN

A

Furosemide

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11
Q

used in treating lithium-induced nephrogenic diabetes insipidus a. Potentiate the action of more proximally acting diuretics b. Counteract the potassium wasting of thiazide and loop diuretics

A

Amiloride

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12
Q

a. Potentiate the action of more proximally acting diuretics b. Counteract the potassium wasting of thiazide and loop diuretics

A

Triamterene

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13
Q

good first choice agent in patients with a significantly enlarged prostate (> 40 g), who cannot tolerate the cardiovascular adverse effects of α1-adrenergic receptor antagonists

A

Finasteride; Dutasteride

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14
Q

BPH

A

Saw palmetto

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15
Q

Prostatitis

A

fluoroquinolones TMP SMX

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16
Q

β2 Agonist activity > β2 Antagonist activity, thus beneficial in treatment of Peripheral Vascular Disease

17
Q

hypertension in pregnancy, & hypertension due to phaechromocytoma

18
Q

Uncomplicated pyelonephritis

A

fluoroquinolones TMP SMX

19
Q

Uncomplicated cystitis

A

Nitrofurantoin Fosfomycin TMP-SMX

20
Q

Anemia of chronic kidney disease

A

Erythropoietic growth factors (epoetin alfa) Ferrous sulfate and ferric gluconate

21
Q

Hypertension (only clinical indication)

A

Losartan, Candesartan, Valsartan, Eprosartan (AT-1 receptor antagonists)

Aliskiren (renin inhibitor)

22
Q

Reduce intracranial pressure in neurological conditions

23
Q

intracavernosal - second line for ED combination therapy - third line for ED

A

Alprostadil

24
Q

Monotherapy can be used as initial therapy with similar response rates to orchiectomy

A

Leuprolide; Goserelin

25
Complicated cystitis
fluoroquinolones
26
can ameliorate the disease flare caused by the initial surge of LH/FSH release when initiating LH-RH agonist therapy For advanced prostate cancer, indicated in combination with an LH-RH agonist
Bicalutamide & flutamide Antiandrogens; Nilutamide
27
Effectively treats hypertension, particularly in the elderly
Nifedipine; Amlodipine; Verapamil; Diltiazem
28
management of hypertensive emergency; administered with diuretic
Sodium nitroprusside Hydralazine Fenoldopam Diazoxide
29
Therapy for hypertension during pregnancy
Methyldopa (Aldomet) Clonidine
30
i. Heart failure ii. Treatment of ascites and edema secondary to hepatic failure iii. Hypokalemic alkalosis secondary to mineralcorticoid excess associated with diminished aldosterone metabolism iv. Effective in secondary hypertension due to hyperaldosteronism a. Potentiate the action of more proximally acting diuretics b. Counteract the potassium wasting of thiazide and loop diuretics
Spironolactone
31
indicated in symptomatic patients with primary or secondary hypogonadism
Testosterone replacement
32
First line for BPH
Alfuzosin, doxazosin, tamsulosin, and terazosin
33
used in combination in with loop diuretics in heart failure a. Diminish hypercalciuria in patients at risk for **nephrolithiasis** b. Hypertension (first-line drugs) c. Heart failure d. Nephrogenic diabetes insipidus
Hydrochlorothiazide and indapamide
34
prevent secondary hyperparathyroidism (sHPT) and subsequent renal osteodystrophy (ROD)
Calcium acetate & calcium carbonate Sevelamer Calcitriol, paricalcitol Cinacalcet
35
single oral dose is effective in the treatment of uncomplicated urinary tract infections (cystitis) in women
Fosfomycin
36
Useful in hypertensive patients with predisposition to, or with asthma, diabetes, or peripheral vascular disease
Metoprolol

Renal Pharm (14 decks)

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