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Renal Pharm > Adverse effects rapid review > Flashcards

Adverse effects rapid review Flashcards

1
Q

neurotoxicity

A

penicillin

cinacalcet secondarty to hypocalcemia

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2
Q

irreversible ototoxicity

A

ethacrynic acid and aminoglycosides

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3
Q

neuromuscular blockade;

A

aminoglycosides; counteracted by calcium salts;

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4
Q

cardiodepresssion

A

verapamil and diltiazem

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5
Q

hot flashes

A 
anti androgens (flutamide etc)
LHRH agonists (goserlin etc)
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6
Q

impotence

A

propranolol
alpha 1 adrenergic (tamsolusin etcv)
lhrh agonists

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7
Q

dry mouth

A

clonidine

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8
Q

hyperphosphatemia

A

calcitriol and parcalcitol

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9
Q

soft tissue and vascular calcification

A

calcitriol and paracalcitol

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10
Q

cardiac arrythmias

A

ethacrynic acid; furosemide; thiazide diuretics

due to hypokalemia

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11
Q

increased bone pain and increased urinary symptoms

A

leuprolide and goserelin

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12
Q

nephropathy

A

ceftriaxone
aminoglycosides
alisikren (renal impairment)

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13
Q

acute hemolytic anemia

A

tmp smx

nitrofurantoin due to g6p def

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14
Q

crystalluria

A

tmp smx

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15
Q

steven johnson

A

tmp smx

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16
Q

kernicterus

A

tmp smx

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17
Q

hyperkalemia

A

alisikren
k sparing diuretics
ace inhibitors

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18
Q

edema

A

calcium channel blockers (nifedpine amlo; verapamil, and diltiazem)
diazoxide
minoxidil;pinacidil
test replacement therpary

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19
Q

treat phaechromocytoma

A

labetolol

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20
Q

treat htn in pregnancy

A

methyldopa clonidine

labetolol

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21
Q

treatz; htn for old people

A

calcium channel blockers; all 4

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22
Q

treat htn in pregnancy

A

methyldopa clonidine

labetolol

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23
Q

treatz; htn for old people

A

calcium channel blockers; all 4

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24
Q

treat htn in pregnancy

A

methyldopa clonidine

labetolol

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25
Q

treatz; htn for old people

A

calcium channel blockers; all 4

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26
Q

treat htn in bph

A

doxazosin and prazosin

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27
Q

polycythemia

A

test replacemtn

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28
Q

contact dermatitis

A

test replacemtn

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29
Q

hepatotoxicity

A

test replacment
anti androgens
azoles

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30
Q

interstitial pneumonitis

A

nilatumide ONLY; ci for respiratory insuff

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31
Q

anaphylaxis

A

ferric gluconate IV

32
Q

orthostatic hypotension

A

alpha 1 adrenergic antagonists (tamsolusin ..etc)
methyldopa
prazosin\doxazosin

33
Q

angioedema

A

arbs such as losartan

ace inhibitors

34
Q

sudden hearing loss on one side; reversible

A

sildenafil etc

35
Q

facial flushing; rhinitis; headache

A

sildenafil etc

36
Q

back and muscle pain

A

sildenafil due to pde11

37
Q

BROWN urine

A

Nitrofurantoin

38
Q

hyperlipidemia

A

Thiazide diuretics

39
Q

hyperuricemia

A

Thiazide diuretics

40
Q

hypokalemia

A

loop diuretics
Thiazide diuretics
causes CARDIAC arythmias

41
Q

accumulation of cyanide byproducts

A

sodium nitroprusside

42
Q

Rebound hypertension on withdrawal

A

Clonidine

Propranalol

43
Q

bradycardia; cardiac conduction problems

A

Propranolol

44
Q

asthma

A

Propranolol

45
Q

hyperglycemia

A

Propranolol
Thiazide diuretics
Loop diuretics

46
Q

hypercalcemia

A

Calcium acetate/carbonate;
Calcitriol; parcalcitol
Thiazides

47
Q

dry cough

A

ACE inhibitors

48
Q

angioedema

A

ACE inhibitors;

ARBs (–tan)

49
Q

Deep vein thrombosis

A

Erythropoeinetin growth factor

50
Q

HYPERtension

A

Erythropoeinetin growth factor

51
Q

Thromboic/vascular events

A

Erythropoeinetin growth factor

52
Q

Hypotension

A

besides the antihypertensives

Ferric gluconate

53
Q

IRON overload

A

Ferric gluconate

54
Q

Gynecomastia

A

Spironolactone

Test replacement
Finasteride/Dutasteride
Antiandrogens

Azoles

55
Q

Rash

A

Penicillin (ampicillin rash)

Azoles

56
Q

Menstrual irregularities

A

Azoles

57
Q

Hepatitis

A

Azoles

58
Q

neurotoxicity such as myoclonus or seizures;

A

Penicillin

59
Q

Irreversible ototoxicity

Neuromuscular blockade

A

Aminoglycosides

60
Q

metabolic acidosis WITHOUT hyperkalemia

A

CA inhibitors; acetazolamide; dorzolamide

61
Q

headache n/v due to hyponatremia

A

mannitol

62
Q

Endocrine-related including hot
flashes, impotence, and decreased
libido

A

Leuprolide

Goserelin

63
Q

used to treat baldness

A

Minoxidil

64
Q

Headache/flushing;
Edema;
Tachycardia/Palpitations,
& Excessive hair growth

A

Minoxidil

65
Q

Effective in 2o hypertension due to hyper-aldosteronism

A

Spironolactone

66
Q

Selective α1-blockade → Arterial dilation

A

Prazosin; doxazosin

67
Q

Central α2-agonism → ↓ Sympathetic tone

A

Clonidine

68
Q

Blocks L-type Ca2+ channels → ↓Ca2+ entry

A

Nifedipine; Amlodipine (Dihydropyridines or DHPs); Verapamil & Diltiazem

69
Q

Opens K+ channels → VSM hyperpolarization & relaxation

A

Minoxidil

70
Q

Donates nitric oxide → ↑cGMP levels (via guanylate cyclase activation)

A

Nitroprusside

71
Q

Opens KATP channels → Hyperpolarization & prolonged dilation

A

Diazoxide

72
Q

Genitourinary: ejaculation disorders
(dry sex or delayed ejaculation) and
erectile dysfunction

A

Finasteride

Dutasteride

73
Q

(dry sex or delayed ejaculation)

A

Finasteride

Dutasteride

74
Q

feminization of a male

fetus

A

Finasteride

Dutasteride

75
Q

Sudden hearing loss usually on one side

involving partial or complete

A

Sildenafil, tadalafil,

vardenafil

76
Q

facial flushing, rhinitis (due to

vasodilation)

A

Sildenafil, tadalafil,

vardenafil

77
Q

Female sexual partners may experience

vaginal burning, itching, or pain

A

Intraurethral Alprostadil

Renal Pharm (14 decks)

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