RPGN Flashcards
1
Q
RPGN is AKA
A
Crescentic GN
2
Q
Population of patients that appear to be particularly prone to CGN
A
Patients with systemic vasculitis
3
Q
Hallmark of CGN
A
Glomerular crescents
4
Q
Crescents in CGN consists of
A
Proliferation of parietal epithelial cells in the Bowman’s space
5
Q
CGN with rare or absent findings on EM and IF
A
1) Pauciimune GN (Wegener disease and microscopic polyangiitis 2) Idiopathic crescentic GN
6
Q
T/F Children with crescentic post-infectious GN can spontaneously recover
A
T
7
Q
May be effective in preventing progressive renal failure in patients with SLE, HSP nephritis, Wegener granulomatosis, and IgA nephropathy if given early in the course when acute cellular crescents predominate
A
High-dose corticosteroids and cyclophosphamide
