HSP Nephritis

Question 1

MC vessel vasculitis in childhood

Answer 1

HSP

Question 2

Approx ___% of patients with HSP develop renal manifestations

Answer 2

50

Question 3

Pathogenesis of HSP nephritis

Answer 3

Deposition of polymeric IgA in glomeruli, indistuinguishable from those if IgA nephropathy

Question 4

When does nephritis in HSP often present?

Answer 4

Weeks to months after onset of rash, may be present at initial presentation, but rarely presents prior to the rash

Question 5

How often should a UA be done in patients with active HSP

Answer 5

Weekly

Question 6

How often should a UA be done in patients after period of active HSP

Answer 6

Monthly for 6 months

Question 7

Prognosis of HSP nephritis for MOST patients

Answer 7

Excellent

Question 8

Untreated, the risk of developing CKD in HSP nephritis is ___%

Answer 8

2-5

Question 9

T/F Tonsillectomy does not appear to have any measurable effect on renal outcome in HSP nephritis

Answer 9

T

Question 10

T/F Mild HSP nephritis does not require treatment

Answer 10

T

Question 11

Severe HSP nephritis is defined as

Answer 11

> 50% crescents on biopsy