RPA - Synthesis Flashcards
1
Q
What is the formula for calculating number of chiral centres?
A
2^n
2
Q
How do you synthesize enantiomerically pure pharmaceuticals?
A
Start with enantiomerically pure natural compounds
use stereoselective catalysis
purify
3
Q
Which two points do you include when asked why a molecule has optical isomers?
A
chiral carbon with 4 groups attached
therefore 2 non-super imposeable mirror images.
4
Q
When identifying molecules that exhibit stereoisomerism, which two forms should you look out for?
A
E/Z and optical
5
Q
Give two reasons why stereoselective synthesis is useful
A
reduced unwanted side effects, increase effectiveness of medicine.
