Role Of Enzymes In Diagnostic Of Bone And Malignant Diseases Flashcards

1
Q

Elevated osteoblastic activity is seen in which enzyme’s elevation

A

Alkaline phophatase (ALP)

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2
Q

Elevated osteoclasts is seen by which enzyme

A

Tartrate-resistant acid phosphatase (TRAP)

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3
Q

In paget disease what enzymes are seen

A

Elevated ALP and TRAP

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4
Q

What is the only isoform that cannot be inhibited by titrate

A

Acip phosphate (ACP)

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5
Q

What enzyme is most specific for liver disease

A

GGT

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6
Q

Where can ALP be found

A

Liver, bile duct and bone

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7
Q

Which enzyme is specific to bones

A

ACP

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8
Q

What are enzymes based tumor markers which examples

A

These are markers utilized in oncology to detect the presence, progression and recurrence of a malignant disease

Proteins
Enzymes
Metabolites

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9
Q

Physical activity can affect which enzyme

A

LDH

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10
Q

What age does ALP levels fluctuate

A

Adolescent

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11
Q

What method distinguishes liver and bone ALP

A

Electrophoresis

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