Enzymes Of Diagnostic Value Flashcards

1
Q

Between AST and ALT which is more domicile in the liver

A

AST

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2
Q

Which enzyme is most prominent in the prostate gland

A

ACP

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3
Q

Which enzyme is prominent in cancer conditions

A

LDH

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4
Q

Why is AST raised after surgery

A

Because of tampering with skeletal muscles

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5
Q

Which LDH isoform is “silent”

A

LDH 4

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6
Q

Which enzyme is responsible for epileptic shock

A

Creatinine kinase CK-BB

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7
Q

Which enzyme is more sensitive that ALP in checking for liver diseases

A

GGT

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8
Q

Which Enzyme is sensitive in diagnosis of pancreatic disorders

A

Lipases

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9
Q

Which enzyme is most indicative of renal disorders

A

Cystatin C

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10
Q

Which enzyme is synthesized by the cells to enter the bloodstream

A

Secretory enzymes

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11
Q

Which enzyme is synthesized by the glands of the GIT

A

Excretory enzymes

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12
Q

What are the cellular compartments where you can find enzymes

A

Cytoplasm
Lysosome
Cellular membrane
Mitochondria

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13
Q

______ transfers amino from amino acid to keto acid

A

Transaminases

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14
Q

Another name for AST IS?

A

Serum oxaloacetate transaminases

SGOT

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15
Q

Another name for ALT?

A

Serum glutamate pyruvate transaminase

SGPT

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16
Q

AST and ALT can be found in ?

A

Skeletal muscle, liver, kidney and electrolytes

17
Q

What enzyme evaluates hepatocellular injury in dog and cats

A

ALT

18
Q

What enzyme is most specific in evaluating hepatic disorders in large animals

A

AST (over ALT)

19
Q

In hepatitis which is higher ALT OR AST

A

ALT

20
Q

Which enzyme is more domicile in the liver?

A

AST

21
Q

______ is a group of enzymes that hydrolysis phosphatase at high pH

A

ALP

22
Q

ALP can be found ?

A

Liver, bones, placenta, intestinal epithelium

23
Q

Intel and extra hepatic cholestases are liver diseases indicative of what enzyme

A

High ALP

24
Q

ACP is found in the ?

A

Prostate gland, liver, bone, platelets and RBCs

25
Q

What does LDH catalyze

A

The reversible interconversion of lactate and pyruvate

26
Q

LDH is found in

A

All cells of the body

27
Q

LDH isoenzymes exist in the body as what ?

A

Tetramers

28
Q

LDH 2 can be seen after?

A

M.I
And
Acute leukemia

29
Q

LDH 1 and LDH 3

A

M.I and acute leukemia respectively

30
Q

Which creatinine kinase isomer is commonly found in the plasma

A

Ck-mm (skeletal muscle)

31
Q

GGT is found in ?

A

Liver, kidney and pancreas

32
Q

What breaks down starch and glycogen to maltose

A

Amylase

33
Q

Amylase is found in

A

Saliva and pancreatic juice

34
Q

Lipases is found where

A

Pancreas

Increase = inflammation/disease of the pancreas

35
Q

Is lipases present in saliva
TRUE/FALSE

A

FALSE