RNA (+) Viruses II

Question 1

Adult rubella is characterized by

Answer 1

Lymphadenopathy, seizures, and arthritis

Question 2

There is no treatment for

Answer 2

Rubella

Question 3

However, there is a Rubella vaccine, which is the live attenuated

Answer 3

MMR vaccine

Question 4

HIV patients should only receive the MMR vaccine if their CD4 counts are above

Answer 4

200

Question 5

Rubella produces one long polyprotein protein precursor that is cleaved by proteases. The BIG BUZZWORD for Rubella is

Answer 5

Immigrant

Question 6

What is the viral classification of corona virus?

Answer 6

Encapsulated SS RNA positive virus

Question 7

What is a major component of the corona viruses?

Answer 7

SARS

Question 8

A helical virus that also causes the common cold

Answer 8

Corona virus

Question 9

SARS and the middle east respiratory syndrome (forms of corona virus) cause

Answer 9

Acute bronchitis

Question 10

All forms of corona virus replicate in the

Answer 10

Cytoplasm

Question 11

Pos Sense RNA Single strand start but then DNA due to reverse transcription

Answer 11

Retroviruses

Question 12

A major form of retrovirus

Answer 12

HIV

Question 13

What is the viral classification of retrovirus?

Answer 13

Encapsulated

Question 14

Diploid nature RNA virus

Answer 14

Retrovirus

Question 15

The capsule for the RNA in a retrovirus is

Answer 15

Gag = p24

Question 16

A transmembrane protein that codes for gp41 and 120

Answer 16

Env protein

Question 17

What are the three important genes for HIV?

Answer 17

Gag, Env, and RT

Question 18

A TORCHeS infection

Answer 18

HIV

Question 19

HIV initially effects

Answer 19

Macrophages

Question 20

Characterized by a prodromal like flu with cervical lymphadenopathy, tonsils may be enlarged. Fever

Answer 20

HIV

Question 21

HIV is latent for 10 years, during which time it is replicating in

Answer 21

Lymph nodes

Question 22

HIV progresses to AIDS when CD4 is below

Answer 22

200

Question 23

HIV enters the macrophages and T Cells via

Answer 23

CCr5 and CXCr4

Question 24

HIV enters the macrophages and T Cells via CCr5 and CXCr4 coreceptors, then will enter, uncoat, undergo

Answer 24

Reverse transcription

Question 25

Elisa is used for screening of HIV and then it is confirmed via

Answer 25

Western blot

Question 26

We measure the viral load of HIV and CD4 count via

Answer 26

PCR

Question 27

All neonates will be positive, but may not actually have the

Answer 27

Disease

Question 28

The backbone of any HART (HIV) therapy is

Answer 28

NRTI’s

Question 29

The best HIV treatment for pregnant patients

Answer 29

Zidovudine

Question 30

Does not incorporate in RNA chain

-Inhibits reverse transcriptase

Answer 30

NNRTI’s

Question 31

Prevents cleavage of proteins for viral replication

Answer 31

Protease inhibitor

Question 32

A CCR5 inhibitor used to treat HIV

Answer 32

Miravoroc