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Sketchy: Viruses > RNA (+) Viruses II > Flashcards

RNA (+) Viruses II Flashcards

1
Q

Adult rubella is characterized by

A

Lymphadenopathy, seizures, and arthritis

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2
Q

There is no treatment for

A

Rubella

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3
Q

However, there is a Rubella vaccine, which is the live attenuated

A

MMR vaccine

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4
Q

HIV patients should only receive the MMR vaccine if their CD4 counts are above

A

200

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5
Q

Rubella produces one long polyprotein protein precursor that is cleaved by proteases. The BIG BUZZWORD for Rubella is

A

Immigrant

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6
Q

What is the viral classification of corona virus?

A

Encapsulated SS RNA positive virus

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7
Q

What is a major component of the corona viruses?

A

SARS

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8
Q

A helical virus that also causes the common cold

A

Corona virus

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9
Q

SARS and the middle east respiratory syndrome (forms of corona virus) cause

A

Acute bronchitis

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10
Q

All forms of corona virus replicate in the

A

Cytoplasm

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11
Q

Pos Sense RNA Single strand start but then DNA due to reverse transcription

A

Retroviruses

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12
Q

A major form of retrovirus

A

HIV

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13
Q

What is the viral classification of retrovirus?

A

Encapsulated

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14
Q

Diploid nature RNA virus

A

Retrovirus

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15
Q

The capsule for the RNA in a retrovirus is

A

Gag = p24

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16
Q

A transmembrane protein that codes for gp41 and 120

A

Env protein

17
Q

What are the three important genes for HIV?

A

Gag, Env, and RT

18
Q

A TORCHeS infection

A

HIV

19
Q

HIV initially effects

A

Macrophages

20
Q

Characterized by a prodromal like flu with cervical lymphadenopathy, tonsils may be enlarged. Fever

A

HIV

21
Q

HIV is latent for 10 years, during which time it is replicating in

A

Lymph nodes

22
Q

HIV progresses to AIDS when CD4 is below

A

200

23
Q

HIV enters the macrophages and T Cells via

A

CCr5 and CXCr4

24
Q

HIV enters the macrophages and T Cells via CCr5 and CXCr4 coreceptors, then will enter, uncoat, undergo

A

Reverse transcription

25
Q

Elisa is used for screening of HIV and then it is confirmed via

A

Western blot

26
Q

We measure the viral load of HIV and CD4 count via

A

PCR

27
Q

All neonates will be positive, but may not actually have the

A

Disease

28
Q

The backbone of any HART (HIV) therapy is

A

NRTI’s

29
Q

The best HIV treatment for pregnant patients

A

Zidovudine

30
Q

Does not incorporate in RNA chain

-Inhibits reverse transcriptase

A

NNRTI’s

31
Q

Prevents cleavage of proteins for viral replication

A

Protease inhibitor

32
Q

A CCR5 inhibitor used to treat HIV

A

Miravoroc

Sketchy: Viruses (6 decks)

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