Risk Factors

Question 1

Fat intake as risk factor for Colorectal adenocarcinoma

Answer 1

Increased FAt intake –> Increased cholesterol and bile acids –> The former can be converted in carcinogens by microbiota

Question 2

Low fiber intake as risk factor for colorectal adenocarcinoma

Answer 2

Low fiber diet –> Low stool bulk –> Mycrobiota toxic products have more contact-time with the mucosa