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BacT JK > Rickettsiales > Flashcards

Rickettsiales Flashcards

1
Q

The order Rickettsiales is a(n) ________________ pathogen:

  1. Facultative intracellular
  2. Obligate intracellular
  3. Extracellular
A
  1. Obligate intracellular
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2
Q

The genus Neorickettsia survive in:

  1. Erythrocytes, phagocytes and platelets
  2. Vascular epithelium
  3. Phagocytes
  4. Macrophages and mononuclear cells
A
  1. Macrophages and mononuclear cells
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3
Q

The genus Rickettsia survive in:

  1. Erythrocytes, phagocytes and platelets
  2. Vascular epithelium
  3. Phagocytes
  4. Macrophages and mononuclear cells
A
  1. Vascular epithelium
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4
Q

The genus Anaplasma survive in:

  1. Erythrocytes, phagocytes and platelets
  2. Vascular epithelium
  3. Phagocytes
  4. Macrophages and mononuclear cells
A
  1. Erythrocytes, phagocytes and platelets
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5
Q

The genus Ehrlichia survive in:

  1. Erythrocytes, phagocytes and platelets
  2. Vascular epithelium
  3. Phagocytes
  4. Macrophages and mononuclear cells
A
  1. Phagocytes
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6
Q

Which reportable bacteria infects ruminants mainly by Boophilus hard ticks and causes destruction of red blood cells and undulant fever?

  1. Rickettsia rickettsii
  2. Anaplasma marginales
  3. Coxiella burnetii
  4. Ehrlichia ruminatium
A
  1. Anaplasma marginales (will also see icterus)
    * Undulant fever due to antigenic variation (Msp2 gene)!
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7
Q

Which bacteria is common in North America that causes Tick Borne Fever in ruminants, horses, dogs, and humans by Ixodes tick bites?

  1. Anaplasma phagocytophilum
  2. Ehrlichia canis
  3. Rickettsia rickettsii
  4. Neorickettsia helminthoeca
A
  1. Anaplasma phagocytophilum
  • Tick Borne Fever = Leukopenia
  • Infection of primarily neutrophils and eosinophils
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8
Q

What disease does Anaplasma platys cause in dogs?

  1. Q fever
  2. Rocky Mountain Spotted Fever
  3. Tick Borne Fever
  4. Infectious Canine Cyclic Thrombocytopenia
A
  1. Infectious Canine Cyclic Thrombocytopenia
  • Undlating fever, petechial hemorrhages, epistaxis (nose bleed)
  • Rhipicephalus and Dermacentor ticks
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9
Q

Which small, non-motile bacteria use invertebrate vectors to enter endothelial cells by endocytosis?

  1. Ehrlichia chaffeensis & ewingii
  2. Neorickettsia helminthoeca
  3. Rickettsia rickettsii
  4. Anaplasma marginales
A
  1. Rickettsia rickettsii
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10
Q

Which bacteria has an endospore-like growth phase, does not need a vector, and causes Q fever (reportable disease) in many species of mammals, including humans.

  1. Coxiella burnetii
  2. Aegyptianella pullorum
  3. Anaplasma marginale
  4. Rickettsia rickettsii
A
  1. Coxiella burnetii (bio-weapon)
  • Q fever = vasculitis and placentitis
  • Persists especially in lactating mammary gland and pregnant uterus; activated during parturition
  • Need to add alkalinizing agents in treatment
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11
Q

T or F. Ehrlichiae is transmitted transovarially and transtadially.

A

F. NOT transovarially

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12
Q

Which disease in dogs causes lymphadenopathy, epistaxis, thrombocytopenia, leukpenia, and its progression occurs mainly in dogs with a genetic predisposition and/or impaired cell-mediated immunity?

  1. Rocky Mountain Spotted Fever
  2. Q fever
  3. Infectious Canine Cyclic Thrombocytopenia
  4. Canine Monocytic Ehrlichiosis
A
  1. Canine Monocytic Ehrlichiosis (Ehrlichia canis)
    * Brown dog tick (Rhipicephalus sanguineus)
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13
Q

What is the vector that transmits Ehrlichia chaffeensis and causes Human Monocytic Ehrlichiosis in the human?

  1. Lone star tick (Amblyoma americanum)
  2. American dog tick (Dermacentor variabilis)
  3. Brown dog tick (Rhipicephalus sanguineus)
  4. Wood tick (Dermacentor andersoni)
A
  1. American dog tick (Dermacentor variabilis)
    * Human Monocytic Ehrlichiosis = human form of Ehrlichia canis
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14
Q

What is the vector that is common in central North America and transmits Ehrlichia ewingii?

  1. Lone star tick (Amblyoma americanum)
  2. American dog tick (Dermacentor variabilis)
  3. Brown dog tick (Rhipicephalus sanguineus)
  4. Wood tick (Dermacentor andersoni)
A
  1. Lone star tick (Amblyoma americanum)
    * Similar disease to Anaplasma phagocytophilum infection
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15
Q

Which reportable disease commonly seen in Africa and the Caribbean is passed only by parenteral introduction to the blood (mainly Amblyomma spp.), and causes vasculitis, hemorrhages, pericardial effusion, edema, and neurological signs in ruminants?

  1. Salmon Poisoning Disease
  2. African Heartwater
  3. Q fever
  4. Tick Borne Fever
A
  1. African Heartwater (Ehrlichia ruminantium)
  • Replicates in reticuloendothelial cells (macrophages, endothelial cells, and neutrophils)
  • Vaccine available
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16
Q

Which genus of the family Anaplasmataceae uses flukes as vectors?

  1. Neorickettsia
  2. Ehrlichia
  3. Anaplasma
  4. Rickettsia
A
  1. Neorickettsia
    * Small, non-motile, coccoid, intracytoplasmic in vacuoles of monocytes, macrophages, and enterocytes
17
Q

Salmon Poisoning Disease (Neorickettsia helminthoeca) in dogs is common only in ___________________.

A

Pacific Northwest

  • Hemorrhagic diarrhea and lymphadenopathy (target cells are mononuclear cells)
  • Case fatality high in untreated dogs
18
Q

What is the main clinical manifestation in the seasonal (summer) disease, Potomac Horse Fever (aka. Equine Scours)?

  1. Anemia
  2. Watery diarrhea
  3. Undulant fever
  4. Neurological signs
A
  1. Watery diarrhea
  • Affinity for blood monocytes, tissue macrophages and intestinal epithelial cells
  • Enterocyte infection with loss of microvilli
  • Intermediate snail reservoir
  • Trematode cercaria
19
Q

What vector carries Aegyptianella pullorum infecting poultry and wild birds with Aegyptianellosis?

A

Ticks of genus Argus

  • Aegyptianellosis = ruffled feathers, diarrhea, anemia, hyperthermia, hepatosplenomegaly
20
Q

Drug of choice for Rickettsiales?

A

Tetracycline

21
Q

Diagnostic test for Anaplasma and Ehrlichia?

A

GIEMSA stain

BacT JK (10 decks)

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