Clicker Q's

Question 1

Properties of mycobacteria include all except:
A. Variable mycolic acid length depending on species.
B. Complete of partial acid fast staining (short vs. long)
C. Presence of lipid compounds in the cell membrane (doesn’t have a cell membrane)
D. May survive at a lower pH
E. Some members are saprophytic

Answer 1

C. Presence of lipid compounds in the cell membrane (Doesn’t have a cell membrane)

Question 2

Which of the following staining method is not an acid-fast stain?
A. Kinyoun’s
B. Zeihl-Neelsen
C. Auramine rhodamine (need fluorescin microscope)
D. Geima

Answer 2

D. Geima

Question 3

T/F. Mycolic acid present in the cell wall of mycobacteria facilitate phagocytosis and removal of mycobacteria.

Answer 3

False.

Question 4

Which of the following mycobacterium is a common cause of zoonotic TB?
A. M. Tuberculosis
B. M. bovis
C. M. paratuberculosis
D. M. lepraemurium

Answer 4

B. M. bovis

Question 5

All of the following animals are reservoirs of M. bovis in certain geographic locations except:
A. Elephants
B. Cattle
C. Badgers
D. Brush tail possums

Answer 5

A. Elephants

Question 6

Which of the following is incorrect about mycobacterium infections?
A. Induce granulomatous inflammation
B. Multinucleated macrophages are common in lesions
C. Caseous necrosis and mineralization may be present in the lesions
D. Humoral immunity helps in protecting from infections

Answer 6

D. Humoral immunity helps in protecting from infections

Question 7

T/F. Combination antimicrobial therapy is essential in the treatment of TB to kill MULTIPLE species of mycobacteria present in a lesion.

Answer 7

False.

Due to resistance and to treat intra and extracellular organisms.

Question 8

Which of the following is incorrect about paucibacillary lesions?
A. Seen in some mycobacterial infections.
B. This is due to lack of cell mediated immunity (less bacteria than a multibacillary lesion).
C. Few bacteria are seen in these lesions.
D. Result in milder disease.

Answer 8

B. This is due to lack of cell mediated immunity (less bacteria than a multibacillary lesions).

Question 9

Use of multiple antimicrobial agents in treating mycobacterial infections is to:
A. To cover multiple species
B. To get more money from the client
C. To minimize development of antimicrobial resistance (and to cover intra and extracellular organisms).
D. To avoid toxicity of using single agent in high doses.

Answer 9

C. To minimize development of antimicrobial resistance (and to cover intra and extracellular organisms).

Question 10

Which of the following mycobacterium species is Mycobactin dependent for its growth?
A. M. bovis
B. M. avium subsp. avium
C. M. lepraemurium
D. M. avium subsp. paratuberculosis

Answer 10

D. M. avium subsp. paratuberculosis (used to diagnose)

Question 11

Which of the following mycobacterium spp. is widely present in soil and water?
A. M. bovis
B. M. leprae
C. M. avium complex
D. M. tuberculosis

Answer 11

C. M. avium complex - opportunistic

Question 12

Properties of mycobacteria include all except:
A. Presence of mycolic acid
B. Positive acid fast stianing
C. Presence of lipid compounds in the cell wall
D. May survive in macrophages
E. All members are obligate pathogens.

Answer 12

E. All members are obligate pathogens.