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BACTE FINALS 3 > RICKETTSIA > Flashcards

RICKETTSIA Flashcards

1
Q

Simplest bacterial form and considered as transitional organism between bacteria and virus.

A

RICKETTSIA

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2
Q

Fastidious bacteria and obligate, intracellular parasites.

A

RICKETTSIA

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3
Q

Rocky mountain spotted fever (RMSF) most
serious rickettsial infection

A

SPOTTED FEVER GROUP:

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4
Q

Gram-negative cell wall, motile, will not grow in
cell-free media

A

RICKETTSIA

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5
Q

Multiply

A

Binary fission

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6
Q

Survive briefly outside of their host

A

RICKETTSIA

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7
Q

Small, pleomorphic, gram-negative
bacilli. They do not undergo any intracellular
developmental cycle

A

Microscopy of RICKETTSIA

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8
Q

R. prowazekii and R.
rickettsii.

A

Agents of bioterrorism

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9
Q

humans are the accidental hosts and
ticks are the main vector and reservoir.

A

Rocky mountain spotted fever

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10
Q

Rashes developed on the palms of the hands
and soles of the feet

A

SPOTTED FEVER GROUP

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11
Q

Rashes that are similar to
RMSF but on face.

A

Boutonneuse fever

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12
Q

(black spot): present in BF

A

Tache noires

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13
Q

rashes face and extremities

A

Rickettsialpox

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14
Q

characterized by rashes on
the face, palms, and soles of feet of the sick.

A

Endemic typhus

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15
Q
  • Rashes are not commonly observed
  • Inhalation of aerosol from dried infected flea
    feces is also a mode of transmission of
    Rickettsia typhi infection.
A

TYPHUS GROUP

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16
Q

Boutonneuse fever
or
Mediterranean
spotted fever

A

Rickettsia
conorii

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17
Q

Ticks
(Rhipicephalu
s sanguineus)

A

Rickettsia
conorii

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18
Q

Rocky Mountain
Spotted Fever

A

Rickettsia
rickettsii

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19
Q

Wood ticks
(Dermacentor andersoni)
Dog ticks
(Dermacentor
variabilis)
Brown Dog
ticks
(Rhipicephalu
s sanguineus
and Amblyomma
cajennense

A

Rickettsia
rickettsii

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20
Q

Rickettsial pox

A

Rickettsia akari

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21
Q

Mouse mite
(Liponyssoide
s sanguineus)

A

Rickettsia akari

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22
Q

Flea-borne spotted
fever

A

Rickettsia felis

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23
Q

Flea bite or
feces

A

Rickettsia felis

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24
Q

Epidemic
typhus/BrillZinsserdisease

A

Rickettsia
prowazekii

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25
Q

Body louse
(Pediculus
humanus
corporis)
Squirrel flea
(Orchopeas
howardi)
Squirrel louse
(Neohematopi
nus
sciuriopteri)

A

Rickettsia
prowazekii

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26
Q

Scrub typhus

A

Orientia
tsutsugamuchi

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27
Q

Chigger
(Leptotrombid
ium deliense)
bite

A

Orientia
tsutsugamuchi

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28
Q

Human Monocytic
ehrlichiosis

A

Ehrlichia
chaffeensis

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29
Q

Lone star tick
(Amblyomma
americanum)

A

Ehrlichia
chaffeensis

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30
Q

Human
granulocytoropic
anaplasmosis

A

Anaplasma
phagocytophila

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31
Q

Deer tick
(Ixodes
scapularis
and Ixodes
pacificus)

A

Anaplasma
phagocytophila

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32
Q

Q fever

A

Coxiella
burnetti

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33
Q

Inhalation of
aerosol and
infected
animals

A

Coxiella
burnetti

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34
Q

Trench fever

A

Bartonella
quintana

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35
Q

Feces of body
louse
(Pediculus
humanus
corporis)

A

Bartonella
quintana

36
Q

Cat scratch disease

A

Bartonella henselae

37
Q

Kitten scratch or bite

A

Bartonella henselae

38
Q

Bacillary
angiomatosis

A

Bartonella henselae

39
Q

Oroya fever and
verruga peruana

A

Bartonella
bacilliformis

40
Q

Sandfly
(Lutzomyia)
bite

A

Bartonella
bacilliformis

41
Q

Categorized as a separate genus due to the
absence of lipopolysaccharide and
peptidoglycan and the presence of 54 to 58 kDa
major surface protein

A

ORIENTIA TSUTSUGAMUSHI

42
Q

t replicates in the cytoplasm of its host cell and
is released through a process that involves
“pinching off” the host cell

A

ORIENTIA TSUTSUGAMUSHI

43
Q

t replicates in the cytoplasm of its host cell and
is released through a process that involves
“pinching off” the host cell

A

MOA of ORIENTIA TSUTSUGAMUSHI

44
Q

Leptotrombidum delicense (Chigger)

A

Vector of ORIENTIA TSUTSUGAMUSHI

45
Q

Leptotrombidum delicense (Chigger)

A

Accidental hosts for ORIENTIA TSUTSUGAMUSHI

46
Q

causes human
granulocytotropic
anaplasmosis

A

ANAPLASMA PHAGOCYTOPHILA

47
Q

Ixodes pacificus
(Western black-legged
tick) and Ixodes scapularis (deer tick)

A

Vector of ANAPLASMA PHAGOCYTOPHILA

48
Q

Peromyscus leucopus (white-footed
mouse)

A

Reservoir of ANAPLASMA PHAGOCYTOPHILA

49
Q

The species of this genus are facultative,
intracellular and Gram-negative bacilli.

A

BARTONELLA

50
Q

They live within the RBC in their natural
mammalian hosts

A

BARTONELLA

51
Q

They live within the RBC in their natural
mammalian hosts

A

BARTONELLA

52
Q

Some species exhibit a “twitching motility in wet
mounts

A

(B. bacilliformis and B. henselae)

53
Q

Trench fever (louse-borne
disease)

A

B. quintana

54
Q

Cat scratch disease

A

B. henselae

55
Q

Infective endocarditis

A

B. elizabethae

56
Q

Oroya fever (chronic
verruga peruana) and
febrile acute haemolytic
anemia

A

B. bacilliformis

57
Q

Cat scratch disease
(secondary agent)

A

B. clarridgeiae

58
Q

Causative agent of Q (Query) fever which is a
systematic infection of the lungs

A

COXIELLA BURNETTI

59
Q

Not transmitted by arthropod vectors

A

COXIELLA BURNETTI

60
Q

Can infect birds and rodents, which in turn
excrete the organisms via their urine, feces and
birth products

A

COXIELLA BURNETTI

61
Q

Can survive extracellularly because of its
endospore-like body

A

COXIELLA BURNETTI

62
Q

Extremely contagious and can be considered as
a potential bioterrorism agent

A

COXIELLA BURNETTI

63
Q

inhalation of contaminated aerosols from
dried animal feces and ingestion of
contaminated unpasteurized milk

A

MOA of COXIELLA BURNETTI

64
Q

Cattle, goats and sheep

A

Animal reservoir of COXIELLA BURNETTI

65
Q

Species of the genus are Gram-negative
coccobacilli that undergo an intracellular
development cycle following the infection of
circulating WBC’s (replicate ion occurs in the
leukocytes)

A

EHRLICHIA

66
Q

Presence of intravacuolar
microcolony that resembles “mulberries” or a
morula

A

MICROSCOPY OF EHRLICHIA

67
Q
  • Elementary body (infective form)
  • Initial bodies
  • Morulae
A

THREE DEVELOPMENTAL STAGES

68
Q

Human and animals (dog and
deer)

A

Natural hosts of EHRLICHIA

69
Q

Amblyomma americanum

A

Primary vector of EHRLICHIA

70
Q

: E. chaffeensis and E. ewingii

A

Species of EHRLICHIA

71
Q

Human monocytic ehrlichiosis

A

Infection of EHRLICHIA

72
Q
  • Immunohistology (Immunofluorescence and
    immunoenzyme stains)
    o Skin biopsy is utilized or usually used.
  • Giemsa stain
A

DIRECT METHODS

73
Q

Yolk sacs of embryonated eggs
and tissue culture

A

Culture media for lab diagnosis of rickettsiaeae

74
Q

isolated from human in an antibiotic-free,
centrifugation-enhanced shell vial cell culture

A

Rickettsia, Ehrlichia and Anaplasma

75
Q

Columbia blood agar with 5% defibrinated blood

A

B. bacilliformis

76
Q

preferred medium for
C. burnetti

A

Lung tissue cells

77
Q

Only test preferred for diagnosis of rickettsial
disease.

A

SEROLOGICAL TEST

78
Q

used to confirm rickettsiosis/ricketsioses
during convalescence stage.

A

SEROLOGICAL TEST

79
Q

Antibodies to rickettsia can be detected until at

A

at
least 2 weeks after the infection.

80
Q

seldom diagnosed serologically
during the acute stage of the illness due to the
absence of an early antibody response

A

Rickettsiosis

81
Q

Gold standard serologic test or reference
method for rickettsioses and Q fever.

A

INDIRECT IMMUNOFLUORESCENT ANTIBODY
(IFA) ASSAY

82
Q

Agglutination of certain strains of Proteus
vulgaris by serum from patient.

A

WEIL-FELIX REACTION

83
Q

Presumptive test for rickettsioses

A

WEIL-FELIX REACTION

84
Q

Individual with Q fever, ehrlichiosis and
rickettsial pox do not produce Weil-Felix
antibody

A

WEIL-FELIX REACTION

85
Q
  • Excellent for detecting antibodies to Rickettsia
  • Used for early diagnosis of RMSF
A

MICROIMMUNOFLUORESCENT DOT TEST

86
Q

can be performed through
PCR testing of lymph nodes.

A

Cat scratch disease

87
Q

diagnostic tool for ehrlichiosis

A

PCR

BACTE FINALS 3 (12 decks)

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