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BACTE FINALS 3 > RICKETTSIA > Flashcards

RICKETTSIA Flashcards

1
Q

Simplest bacterial form and considered as transitional organism between bacteria and virus.

A

RICKETTSIA

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2
Q

Fastidious bacteria and obligate, intracellular parasites.

A

RICKETTSIA

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3
Q

Rocky mountain spotted fever (RMSF) most
serious rickettsial infection

A

SPOTTED FEVER GROUP:

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4
Q

Gram-negative cell wall, motile, will not grow in
cell-free media

A

RICKETTSIA

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5
Q

Multiply

A

Binary fission

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6
Q

Survive briefly outside of their host

A

RICKETTSIA

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7
Q

Small, pleomorphic, gram-negative
bacilli. They do not undergo any intracellular
developmental cycle

A

Microscopy of RICKETTSIA

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8
Q

R. prowazekii and R.
rickettsii.

A

Agents of bioterrorism

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9
Q

humans are the accidental hosts and
ticks are the main vector and reservoir.

A

Rocky mountain spotted fever

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10
Q

Rashes developed on the palms of the hands
and soles of the feet

A

SPOTTED FEVER GROUP

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11
Q

Rashes that are similar to
RMSF but on face.

A

Boutonneuse fever

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12
Q

(black spot): present in BF

A

Tache noires

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13
Q

rashes face and extremities

A

Rickettsialpox

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14
Q

characterized by rashes on
the face, palms, and soles of feet of the sick.

A

Endemic typhus

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15
Q
  • Rashes are not commonly observed
  • Inhalation of aerosol from dried infected flea
    feces is also a mode of transmission of
    Rickettsia typhi infection.
A

TYPHUS GROUP

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16
Q

Boutonneuse fever
or
Mediterranean
spotted fever

A

Rickettsia
conorii

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17
Q

Ticks
(Rhipicephalu
s sanguineus)

A

Rickettsia
conorii

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18
Q

Rocky Mountain
Spotted Fever

A

Rickettsia
rickettsii

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19
Q

Wood ticks
(Dermacentor andersoni)
Dog ticks
(Dermacentor
variabilis)
Brown Dog
ticks
(Rhipicephalu
s sanguineus
and Amblyomma
cajennense

A

Rickettsia
rickettsii

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20
Q

Rickettsial pox

A

Rickettsia akari

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21
Q

Mouse mite
(Liponyssoide
s sanguineus)

A

Rickettsia akari

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22
Q

Flea-borne spotted
fever

A

Rickettsia felis

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23
Q

Flea bite or
feces

A

Rickettsia felis

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24
Q

Epidemic
typhus/BrillZinsserdisease

A

Rickettsia
prowazekii

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25
Body louse (Pediculus humanus corporis) Squirrel flea (Orchopeas howardi) Squirrel louse (Neohematopi nus sciuriopteri)
Rickettsia prowazekii
26
Scrub typhus
Orientia tsutsugamuchi
27
Chigger (Leptotrombid ium deliense) bite
Orientia tsutsugamuchi
28
Human Monocytic ehrlichiosis
Ehrlichia chaffeensis
29
Lone star tick (Amblyomma americanum)
Ehrlichia chaffeensis
30
Human granulocytoropic anaplasmosis
Anaplasma phagocytophila
31
Deer tick (Ixodes scapularis and Ixodes pacificus)
Anaplasma phagocytophila
32
Q fever
Coxiella burnetti
33
Inhalation of aerosol and infected animals
Coxiella burnetti
34
Trench fever
Bartonella quintana
35
Feces of body louse (Pediculus humanus corporis)
Bartonella quintana
36
Cat scratch disease
Bartonella henselae
37
Kitten scratch or bite
Bartonella henselae
38
Bacillary angiomatosis
Bartonella henselae
39
Oroya fever and verruga peruana
Bartonella bacilliformis
40
Sandfly (Lutzomyia) bite
Bartonella bacilliformis
41
Categorized as a separate genus due to the absence of lipopolysaccharide and peptidoglycan and the presence of 54 to 58 kDa major surface protein
ORIENTIA TSUTSUGAMUSHI
42
t replicates in the cytoplasm of its host cell and is released through a process that involves “pinching off” the host cell
ORIENTIA TSUTSUGAMUSHI
43
t replicates in the cytoplasm of its host cell and is released through a process that involves “pinching off” the host cell
MOA of ORIENTIA TSUTSUGAMUSHI
44
Leptotrombidum delicense (Chigger)
Vector of ORIENTIA TSUTSUGAMUSHI
45
Leptotrombidum delicense (Chigger)
Accidental hosts for ORIENTIA TSUTSUGAMUSHI
46
causes human granulocytotropic anaplasmosis
ANAPLASMA PHAGOCYTOPHILA
47
Ixodes pacificus (Western black-legged tick) and Ixodes scapularis (deer tick)
Vector of ANAPLASMA PHAGOCYTOPHILA
48
Peromyscus leucopus (white-footed mouse)
Reservoir of ANAPLASMA PHAGOCYTOPHILA
49
The species of this genus are facultative, intracellular and Gram-negative bacilli.
BARTONELLA
50
They live within the RBC in their natural mammalian hosts
BARTONELLA
51
They live within the RBC in their natural mammalian hosts
BARTONELLA
52
Some species exhibit a “twitching motility in wet mounts
(B. bacilliformis and B. henselae)
53
Trench fever (louse-borne disease)
B. quintana
54
Cat scratch disease
B. henselae
55
Infective endocarditis
B. elizabethae
56
Oroya fever (chronic verruga peruana) and febrile acute haemolytic anemia
B. bacilliformis
57
Cat scratch disease (secondary agent)
B. clarridgeiae
58
Causative agent of Q (Query) fever which is a systematic infection of the lungs
COXIELLA BURNETTI
59
Not transmitted by arthropod vectors
COXIELLA BURNETTI
60
Can infect birds and rodents, which in turn excrete the organisms via their urine, feces and birth products
COXIELLA BURNETTI
61
Can survive extracellularly because of its endospore-like body
COXIELLA BURNETTI
62
Extremely contagious and can be considered as a potential bioterrorism agent
COXIELLA BURNETTI
63
inhalation of contaminated aerosols from dried animal feces and ingestion of contaminated unpasteurized milk
MOA of COXIELLA BURNETTI
64
Cattle, goats and sheep
Animal reservoir of COXIELLA BURNETTI
65
Species of the genus are Gram-negative coccobacilli that undergo an intracellular development cycle following the infection of circulating WBC’s (replicate ion occurs in the leukocytes)
EHRLICHIA
66
Presence of intravacuolar microcolony that resembles “mulberries” or a morula
MICROSCOPY OF EHRLICHIA
67
* Elementary body (infective form) * Initial bodies * Morulae
THREE DEVELOPMENTAL STAGES
68
Human and animals (dog and deer)
Natural hosts of EHRLICHIA
69
Amblyomma americanum
Primary vector of EHRLICHIA
70
: E. chaffeensis and E. ewingii
Species of EHRLICHIA
71
Human monocytic ehrlichiosis
Infection of EHRLICHIA
72
* Immunohistology (Immunofluorescence and immunoenzyme stains) o Skin biopsy is utilized or usually used. * Giemsa stain
DIRECT METHODS
73
Yolk sacs of embryonated eggs and tissue culture
Culture media for lab diagnosis of rickettsiaeae
74
isolated from human in an antibiotic-free, centrifugation-enhanced shell vial cell culture
Rickettsia, Ehrlichia and Anaplasma
75
Columbia blood agar with 5% defibrinated blood
B. bacilliformis
76
preferred medium for C. burnetti
Lung tissue cells
77
Only test preferred for diagnosis of rickettsial disease.
SEROLOGICAL TEST
78
used to confirm rickettsiosis/ricketsioses during convalescence stage.
SEROLOGICAL TEST
79
Antibodies to rickettsia can be detected until at
at least 2 weeks after the infection.
80
seldom diagnosed serologically during the acute stage of the illness due to the absence of an early antibody response
Rickettsiosis
81
Gold standard serologic test or reference method for rickettsioses and Q fever.
INDIRECT IMMUNOFLUORESCENT ANTIBODY (IFA) ASSAY
82
Agglutination of certain strains of Proteus vulgaris by serum from patient.
WEIL-FELIX REACTION
83
Presumptive test for rickettsioses
WEIL-FELIX REACTION
84
Individual with Q fever, ehrlichiosis and rickettsial pox do not produce Weil-Felix antibody
WEIL-FELIX REACTION
85
* Excellent for detecting antibodies to Rickettsia * Used for early diagnosis of RMSF
MICROIMMUNOFLUORESCENT DOT TEST
86
can be performed through PCR testing of lymph nodes.
Cat scratch disease
87
diagnostic tool for ehrlichiosis
PCR

BACTE FINALS 3 (12 decks)

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