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BACTE FINALS 3 > CHLAMYDIA > Flashcards

CHLAMYDIA Flashcards

1
Q

Genus are non-motile, small (0.2to1.5um) and
have Gram-negative cell wall

A

CHLAMYDIACEAE

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2
Q

Do not possess cytochromes and cannot
synthesize their own ATP.

A

CHLAMYDIACEAE

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3
Q

They are called “energy parasites” because they
depend on the eukaryotic cells of their host for
metabolism, growth and reproduction.

A

CHLAMYDIACEAE

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4
Q

Replicate by binary fission in the cytoplasm of
infected cells

A

CHLAMYDIACEAE

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5
Q

Obligate, intracellular organisms that requires
living cells for growth

A

CHLAMYDIACEAE

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6
Q

replicative and non-infectious form

A

RETICULATE BODY (RB)

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7
Q
  • Intracellular and metabolically active form of
    Chlamydia.
  • Multiply: Binary fission
A

RETICULATE BODY (RB)

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8
Q

Infectious form

A

ELEMENTARY BODY (EB)

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9
Q
  • Extracellular from a Chlamydia and is spherical
    in shape.
  • Resembles Gram-negative bacilli with a rigid cell
    wall
A

ELEMENTARY BODY (EB)

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10
Q

Infects cells through inducing active
phagocytosis

A

ELEMENTARY BODY (EB)

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11
Q
  • Major sexually transmitted pathogen
A

CHLAMYDIA TRACHOMATIS

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12
Q

PID (pelvic inflammatory
disease) and ocular trachoma

A

PRINCIPAL CAUSE IN CHLAMYDIA TRACHOMATIS

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13
Q
  • Travel through the birth canal where infants can
    be infected during birth
  • Associated within fertility and ectopic pregnancy
A

CHLAMYDIA TRACHOMATIS

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14
Q

Natural host

A

Humans

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15
Q

Unique features

A

10 stable plasmids

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16
Q

Lymphogranuloma venereum (LGV),
mouse and pneumonitis trachoma

A

bIOVARS

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17
Q

Serotypes A, B, Ba, C:

A

endemic trachoma

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18
Q

Serotypes L1, L2, L2a,
L2b, L3 –

A

LGV

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19
Q

Serotypes D to K, Da,
Ia, Ja

A

PID, urethritis,
cervicitis, epididymitis
and inclusion
conjunctivitis

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20
Q

Chronic inflammation of the
conjunctiva that lead to
blindness

A

TRACHOMA

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21
Q

Cause distortion of the eyelids
(eyelashes become
misdirected and turned-in)

A

TRACHOMA

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22
Q

Contact with contaminated objects, hand
to hand contact with
carriers and through
vectors (flies)

A

MOT FOR CHLAMYDIA TRACHOMATIS

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23
Q

Sexually transmitted
disease which has a multi-system involvement

A

LYMPHOGRANULOMA
VENEREUM (LGV)

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24
Q

Small, painless ulcer or papule appears initially
and then nodules (buboes) develop after several
weeks

A

LYMPHOGRANULOMA
VENEREUM (LGV)

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25
Q

Characterized by an abundant eye discharge
and swollen conjunctiva

A

INCLUSION CONJUNCTIVITIS

26
Q

Affects infants who acquired it through aspiration
or ocular exposure during birth

A

INCLUSION CONJUNCTIVITIS

27
Q

Urethra and cervical secretions,
conjunctiva discharge, nasopharynx and rectal
swabs and material aspirated from fallopian
tubes and epididymis

A

sPECIMEN USED FOR C. TRACHOMATIS

28
Q

PREFERRED SPECIMEN FOR C TRACHOMATIS

A

Dacron and rayon-tipped swabs

29
Q

Buffalo green monkey kidney
cells, He La 299 cells, Hep-2 cells, McCoy cells
and Cyclohexamide-treated McCoy cells.

A

CULTURE MEDIA FOR C TRACHOMATIS

30
Q

Cell scrapings from conjunctiva of newborns or
persons with ocular trachoma.
Direct fluorescent antibody (DFA)

A

CYTOLOGIC EXAMINATION

31
Q

Fluorescein-isothiocyanate-conjugated
monoclonal antibofy

A

Direct fluorescent antibody (DFA)

32
Q

most sensitive
method for detection of C. trachomatis

A

Nucleic acid amplification

33
Q

Endocervical and urethral swabs

A

sPECIMEN IN ANTIGEN DETECTION AND NAAT

34
Q

that is detected

A

LPS antigen major antigen

35
Q

Extractable LPS and elementary body with ketodeoxyoctonate is the primary antigen that can be
identified in genus specific test.

A

SERODIAGNOSIS

36
Q

exclude chlamydial infection

A

negative test

37
Q

family-reactive
antibodies. Used to diagnosed LGV.

A

Complement fixation

38
Q

family-reactive
antibodies. Used to diagnosed LGV.

A

> 1:64

39
Q

Used for type-specific
antibodies of C. trachomatis

A

Microimmunofluorescence (MICROIF) Assay

40
Q

Preferred method for
identification of C. trachomatis

A

Microimmunofluorescence (MICROIF) Assay

41
Q

It can be used for the diagnosis
of LGV, trachoma, inclusion
conjunctivitis, and chlamydial
neonatal infection

A

Microimmunofluorescence (MICROIF) Assay

42
Q

IgM titer of 1:32

A

positive for microimmunofluorescence assay

43
Q

Most commonly
used rapid antigen assay

A

Enzyme immunoassay (EIA):

44
Q

Detects the outer membrane LPS chlamydial
antigen or MOMP antigen

A

Enzyme immunoassay (EIA):

45
Q

Causative agent of psittacosis or ornithosis

A

CHLAMYDOPHILA PSITTACI

46
Q

Endemic pathogen of birds’ specie such as
parrots, parakeets, chicken and ducks

A

CHLAMYDOPHILA PSITTACI

47
Q

Inhalation of infected aerosols from dried
bird excreta or handling of infected birds

A

MOA of CHLAMYDOPHILA PSITTACI

48
Q

Complement fixation
with titer of >1:32

A

Commonly used test for chlamydophila psittaci

49
Q

Direct
microimmunofluorescence

A

Sensitive method for chlamydophila psittaci

50
Q

Only laboratories
with biosafety level 3 facilities can perform the
isolation and cultivation of the specimens

A

Precautionary measures for chlamydophila psittaci

51
Q

Formerly known as the Chlamydia pneumonia
strain TWAR.
o TWAR – Taiwan Acute Respiratory
Chlamydia

A

CHLAMYDOPHILA PNEUMONIAE

52
Q

Human pathogen that is transmitted through
aerosol droplets.

A
53
Q

Human pathogen that is transmitted through
aerosol droplets.

A

CHLAMYDOPHILA PNEUMONIAE

54
Q

Associated with pneumonia, bronchitis,
pharyngitis and sinusitis

A

CHLAMYDOPHILA PNEUMONIAE

55
Q

Nasopharyngeal
aspirates, sputum and throat swabs

A

Specimen for isolation for chlamydophila pneumoniae

56
Q

: He LA cells or Hep-2 cell lines

A

culture media for for chlamydophila pneumoniae

57
Q

Microimmunofluorescent
assay

A

Preferred method for chlamydophila pneumoniae

58
Q

Ducks, pigeon, hen, sparrow, cockatiels,
macaws, budgerigars

A

PARROT DISEASE/ Psittacosis (1929)

59
Q

Zoonotic disease acquired by humans through
inhalation of dried excreta of animals or infected
birds.

A

Psittacosis (1929)

60
Q

mild flu, lung infection

A

caused by Psittacosis (1929)

61
Q

Also known as Ornithosis or Chlamydiosis

A

Psittacosis (1929)

BACTE FINALS 3 (12 decks)

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