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BACTE FINALS 3 > CHLAMYDIA > Flashcards

CHLAMYDIA Flashcards

1
Q

Genus are non-motile, small (0.2to1.5um) and
have Gram-negative cell wall

A

CHLAMYDIACEAE

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2
Q

Do not possess cytochromes and cannot
synthesize their own ATP.

A

CHLAMYDIACEAE

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3
Q

They are called “energy parasites” because they
depend on the eukaryotic cells of their host for
metabolism, growth and reproduction.

A

CHLAMYDIACEAE

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4
Q

Replicate by binary fission in the cytoplasm of
infected cells

A

CHLAMYDIACEAE

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5
Q

Obligate, intracellular organisms that requires
living cells for growth

A

CHLAMYDIACEAE

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6
Q

replicative and non-infectious form

A

RETICULATE BODY (RB)

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7
Q
  • Intracellular and metabolically active form of
    Chlamydia.
  • Multiply: Binary fission
A

RETICULATE BODY (RB)

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8
Q

Infectious form

A

ELEMENTARY BODY (EB)

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9
Q
  • Extracellular from a Chlamydia and is spherical
    in shape.
  • Resembles Gram-negative bacilli with a rigid cell
    wall
A

ELEMENTARY BODY (EB)

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10
Q

Infects cells through inducing active
phagocytosis

A

ELEMENTARY BODY (EB)

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11
Q
  • Major sexually transmitted pathogen
A

CHLAMYDIA TRACHOMATIS

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12
Q

PID (pelvic inflammatory
disease) and ocular trachoma

A

PRINCIPAL CAUSE IN CHLAMYDIA TRACHOMATIS

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13
Q
  • Travel through the birth canal where infants can
    be infected during birth
  • Associated within fertility and ectopic pregnancy
A

CHLAMYDIA TRACHOMATIS

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14
Q

Natural host

A

Humans

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15
Q

Unique features

A

10 stable plasmids

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16
Q

Lymphogranuloma venereum (LGV),
mouse and pneumonitis trachoma

A

bIOVARS

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17
Q

Serotypes A, B, Ba, C:

A

endemic trachoma

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18
Q

Serotypes L1, L2, L2a,
L2b, L3 –

A

LGV

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19
Q

Serotypes D to K, Da,
Ia, Ja

A

PID, urethritis,
cervicitis, epididymitis
and inclusion
conjunctivitis

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20
Q

Chronic inflammation of the
conjunctiva that lead to
blindness

A

TRACHOMA

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21
Q

Cause distortion of the eyelids
(eyelashes become
misdirected and turned-in)

A

TRACHOMA

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22
Q

Contact with contaminated objects, hand
to hand contact with
carriers and through
vectors (flies)

A

MOT FOR CHLAMYDIA TRACHOMATIS

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23
Q

Sexually transmitted
disease which has a multi-system involvement

A

LYMPHOGRANULOMA
VENEREUM (LGV)

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24
Q

Small, painless ulcer or papule appears initially
and then nodules (buboes) develop after several
weeks

A

LYMPHOGRANULOMA
VENEREUM (LGV)

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25
Characterized by an abundant eye discharge and swollen conjunctiva
INCLUSION CONJUNCTIVITIS
26
Affects infants who acquired it through aspiration or ocular exposure during birth
INCLUSION CONJUNCTIVITIS
27
Urethra and cervical secretions, conjunctiva discharge, nasopharynx and rectal swabs and material aspirated from fallopian tubes and epididymis
sPECIMEN USED FOR C. TRACHOMATIS
28
PREFERRED SPECIMEN FOR C TRACHOMATIS
Dacron and rayon-tipped swabs
29
Buffalo green monkey kidney cells, He La 299 cells, Hep-2 cells, McCoy cells and Cyclohexamide-treated McCoy cells.
CULTURE MEDIA FOR C TRACHOMATIS
30
Cell scrapings from conjunctiva of newborns or persons with ocular trachoma. Direct fluorescent antibody (DFA)
CYTOLOGIC EXAMINATION
31
Fluorescein-isothiocyanate-conjugated monoclonal antibofy
Direct fluorescent antibody (DFA)
32
most sensitive method for detection of C. trachomatis
Nucleic acid amplification
33
Endocervical and urethral swabs
sPECIMEN IN ANTIGEN DETECTION AND NAAT
34
that is detected
LPS antigen major antigen
35
Extractable LPS and elementary body with ketodeoxyoctonate is the primary antigen that can be identified in genus specific test.
SERODIAGNOSIS
36
exclude chlamydial infection
negative test
37
family-reactive antibodies. Used to diagnosed LGV.
Complement fixation
38
family-reactive antibodies. Used to diagnosed LGV.
> 1:64
39
Used for type-specific antibodies of C. trachomatis
Microimmunofluorescence (MICROIF) Assay
40
Preferred method for identification of C. trachomatis
Microimmunofluorescence (MICROIF) Assay
41
It can be used for the diagnosis of LGV, trachoma, inclusion conjunctivitis, and chlamydial neonatal infection
Microimmunofluorescence (MICROIF) Assay
42
IgM titer of 1:32
positive for microimmunofluorescence assay
43
Most commonly used rapid antigen assay
Enzyme immunoassay (EIA):
44
Detects the outer membrane LPS chlamydial antigen or MOMP antigen
Enzyme immunoassay (EIA):
45
Causative agent of psittacosis or ornithosis
CHLAMYDOPHILA PSITTACI
46
Endemic pathogen of birds’ specie such as parrots, parakeets, chicken and ducks
CHLAMYDOPHILA PSITTACI
47
Inhalation of infected aerosols from dried bird excreta or handling of infected birds
MOA of CHLAMYDOPHILA PSITTACI
48
Complement fixation with titer of >1:32
Commonly used test for chlamydophila psittaci
49
Direct microimmunofluorescence
Sensitive method for chlamydophila psittaci
50
Only laboratories with biosafety level 3 facilities can perform the isolation and cultivation of the specimens
Precautionary measures for chlamydophila psittaci
51
Formerly known as the Chlamydia pneumonia strain TWAR. o TWAR – Taiwan Acute Respiratory Chlamydia
CHLAMYDOPHILA PNEUMONIAE
52
Human pathogen that is transmitted through aerosol droplets.
53
Human pathogen that is transmitted through aerosol droplets.
CHLAMYDOPHILA PNEUMONIAE
54
Associated with pneumonia, bronchitis, pharyngitis and sinusitis
CHLAMYDOPHILA PNEUMONIAE
55
Nasopharyngeal aspirates, sputum and throat swabs
Specimen for isolation for chlamydophila pneumoniae
56
: He LA cells or Hep-2 cell lines
culture media for for chlamydophila pneumoniae
57
Microimmunofluorescent assay
Preferred method for chlamydophila pneumoniae
58
Ducks, pigeon, hen, sparrow, cockatiels, macaws, budgerigars
PARROT DISEASE/ Psittacosis (1929)
59
Zoonotic disease acquired by humans through inhalation of dried excreta of animals or infected birds.
Psittacosis (1929)
60
mild flu, lung infection
caused by Psittacosis (1929)
61
Also known as Ornithosis or Chlamydiosis
Psittacosis (1929)

BACTE FINALS 3 (12 decks)

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