POTENTIAL VIRULENCE FACTORS OF ANAEROBIC BACTERIA Flashcards
Promotes abscess formation;
antiphagocytic function
Polysaccharide capsules
Fimbriae, fibrils enable organisms to
adhere to cell surfaces
Adherence factors
Bacteroides fragilis, Porphyromonas
gingivalis
Polysaccharide capsules ANAEROBES KNOWN OR
THOUGHT TO POSSESS
B. fragilis, P. gingivalis
Adherence factors ANAEROBES KNOWN OR
THOUGHT TO POSSESS
Catalyze the degradation of collagen
Collagenases
Toxic to specific types of cells
Cytotoxins
Destroy DNA
DNases
Toxic to cells of the intestinal mucosa
Enterotoxin
Lyse red blood cells liberating
hemoglobin
Hemolysins
Catalyzes the hydrolysis of hyaluronic
acid, the cement substance of tissues
Hyaluronidase
Catalyze the hydrolysis of ester
linkages between fatty acids and
glycerol of triglycerides and
phospholipids
Lipases
Destroy or disrupt nerve tissue
Neurotoxins (e.g., botulinum toxin,
tetanospasmin)
Catalyze the splitting of host
phospholipids (lecithinase)
Phospholipases
Split host proteins by hydrolysis of
peptide bonds
Proteases