Rhogam 😻😻

Question 1

What is rhogam

Answer 1

Rho(D) immune globulin (RhIG) is a medication used to prevent RhD isoimmunization in mothers who are RhD negative and to treat idiopathic thrombocytopenic purpura (ITP) in people who are Rh positive.

Prevention of anti Rh(d) antibody formation is most successful if the medication is administered twice as 28 weeks of gestation and again within 72 hours after delivering

Question 2

State the mechanism of action of rhogram

Answer 2

Blocks Rh antigen of fetal cells

Antigen coated red blood cells are removed through maternal circulation

Central inhibition-interfere the production of IgG from B cells.

Question 3

State the dosage of rhogam.[ No uterine bleeding]

Answer 3

<13 wk gestation: 50mcg IM
>13 wk gestation: 300mcg IM

Question 4

In uterine bleeding give what dose of rhogam

Answer 4

300ug per 30ml fetal whole blood or 15ml pRBC.

Question 5

State the administration for Rhogram

Answer 5

First shot around 28 week
Second within 72 hours following delivery or abortion
Maybe giving up to 14 to 18 days after delivery to avoid sensitisation.

Question 6

State the indication for rhogam

Answer 6

To prevent ISO immunization of RH negative client exposed to RH positive
MTP
Abdominal trauma bleeding during pregnancy

Question 7

State the adverse effect of rhogram

Answer 7

Elevated temperature
Tenderness

Question 8

State the contraindications of rhogram

Answer 8

RH positive woman
Patient with allergic reactions