Anticonvulsants 😤😤 Flashcards
What is anticonvulsants
Are drugs used to treat seizures in pregnancy
State the drugs that are anticonvulsants
Magnesium sulphate
Diazepam
Phenytoin
State the mode of action of magnesium sulphate
It decreases the ACH release from the nerve endings
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reduces the motor and plate sensitivity
Give the dosage for magnesium sulphate
IM 4 gm to 10 gm
IV 4 to 6gm
State the indications for magnesium sulphate
Prevention or control of seizures in preeclampsia and eclampsia
Hypomagnesia
State the side effects of magnesium sulpate on the maternal
Muscular paresis
Respiratory failure
State the side effects of magnesium sulphate on the fetal
Respiratory depression
Motor depression
Birth hypotonea
Thermoregulatory problem in newborn
What is phenytoin
It is a centrally acting anticonvulsants
State the mode of action of phenytoin
Pronounce inactivation state of Na+ channels
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Reducing likelihood of repetitive discharge
State the indication for phenytoin
Prevention or control of seizures in preeclampsia and eclampsia general tonic- clonic, partial[ status epilepticus ]
State the side effects of phenytoin on the maternal
Occular
Ataxia[sedation]
Gingival hyperplasia
State the contraindication for phenytoin
Patient with myasthenia gravis an impended renal function.
Magnesium sulfate injection should not be administer parenterally in patient with heart block all myocardial damage.
State the mode of action of diazepam
Depresses sulbcortical levels of CNS anti-anxiety
State the dosage and routes of administration of diazepam
P0: 2 to 10mg t.i.d - q.i.d.
IV: 20mg(bolus), 2mg/min not to exceed 60mg.
State the side effects of diazepam on the maternal
Hypotension
dizziness
drowsiness
headache
