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Drugs Used In Pregnancy Labour Pueperium And Newborn πŸ’ŠπŸ’ŠπŸ’Š > Antihypertensive πŸ”₯πŸ”₯ > Flashcards

Antihypertensive πŸ”₯πŸ”₯ Flashcards

1
Q

What is antihypertensives

A

Are drugs given when BP is 160/110mm of Hg to protect mother from cerebral hemorrhage, cardiac failure, placenta abruption

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2
Q

What is the first line therapy of antihypertensive

A

Methyldopa
Nifedipine(2nd)

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3
Q

What is the mode of action of antihypertensives

A

Change in myometrial cell membranepermeability
|
or alteration of the membrane band calcium
|
then they synthesize myometrium to produce uterine contractions

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4
Q

State the indication of anti hypertensive

A

1.Induction of abortion
2.Induction of labor
3.acceleration of labor management of 4.atonic postpartum hemorrhage
5.Termination of molar pregnancy
6.Management of ectopic tubal pregnancy

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5
Q

State the contraindication of antihypertensive

A

1.Hypersensitivity to drugs
2.uterus scar
3.pelvic inflammatory disease
4.hepatic and renal disorder

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6
Q

State the side effects of antihypertensive

A
  1. Reproductive system: uterine rupture
  2. Vascular disorder: hypertension
  3. Pregnancy puerperium and perinatal conditions: amniotic fluid embolism
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7
Q

State eight antihypertensive drugs

A
  1. Methyldopa
    2.Labetalol
    3.Nifedipine
    4.prazocin
    5.propranol
    6.sodium Nitroprusside
    7.diuretics
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8
Q

State the mode of methyldopa

A

Stimulate Central 𝛂-adrenergic receptors
|
Resulting in decrease of arterial pressure

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9
Q

State the dose of methyldopa

A

Orally- 250mg - 500mg
IV -250mg - 500mg

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10
Q

State the indication for antihypertensive

A

1.Hypertension
2. Gestational hypertension (PIH)
3. Preeclampsia

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11
Q

State the side effects of antihypertensive drugs on the mother

A

Postural hypertension
hemolytic anemia
Sodium retention

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12
Q

State the side effects of antihypertensive drugs on the fetus

A

Intestinal illeus

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13
Q

State the contraindication for antihypertensive drugs

A

Hepatic disorders
Psychic patients
CCF

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14
Q

State the mode of action of labetalol

A

Decrease in systematic arterial blood pressure and systemic vascular resistance
|
because of its combine 𝛂-Ξ²-adrenergic blocking activity

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15
Q

State the indication for labetalol

A

Hypertension
Severe hypertension
Hypertensive emergencies

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16
Q

Side effects of labetalol on the mother and fetal

A

Postural hypotension
sodium retention
intestinal ilieus

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17
Q

State the contraindication for labetalol

A

Hepatic disorders

18
Q

State the dosage for labetalol

A

Orally:100mg t.i.d.
IV: 1-2mg/min until desired results

19
Q

What is propanol (1NN)

A

Is a sympatholytic non- selective beta blocker

20
Q

State the mode of action of propanol

A

A non selective better blocker that reduces cardiac oxygen demand
|
by blocking catecholamine-induced increases in heart rate blood pressure and force of myocardial contraction

21
Q

State the dosage of propranol

A

Orally 80 to 240 mg

22
Q

What is the indication for propranol

A

Hypertension

23
Q

State the side effects of propranol on the maternal

A

Severe hypotension
Sodium retention
Bradycardia
Bronchospasm
Cardiac failure
Hypoglycemia

24
Q

State the side effects of propranol on the fetal

A

Bradycardia
Impaired fetal response to hypoxia
IUGR(intrauterine growth restriction) when began a first and second trimester
Neonatal hypoglycemia
bronchial asthma
Renal insufficiency
diabetes

25
Q

Contraindications for propranol

A

Bronchial asthma
Cardiogenic shock

26
Q

What is prazosin

A

It is a sympatholytic drug used to treat high blood pressure

27
Q

State the dosage of prazosin

A

Orally: 1 mg b.i.d

28
Q

What is the indication for prazosin

A

Hypertension

29
Q

State the side effects prazosin

A

Hypotension
Nasal congestion
Fluid retention

30
Q

State the contraindication of prazosin

A

Hypotension
Syncope

31
Q

What is nifedipine

A

It is a diehydro pyridine calcium Channel blocker

32
Q

State the mode of action of nifedipine

A

Calcium Channel blockers
(Nifedipine)
|
Block the entry of calcium ions from ECF to ICF
|
Reduces the contractilty of muscles

33
Q

State the dose of nifedipine

A

Orally 5 to 10 mg

34
Q

State the indication for nifedipine

A

Pre term labor
Hypertension
Chronic or stable angina

35
Q

State the side effects of nifedipine

A

Flushing
Hypotension
Headache
Tachycardia
Inhibition of labor
Bradycardia
Ankle edema
Constipation
Placenta ischemia
heart block

36
Q

State the contraindications of nifedipine

A

It could be hazardous due to his synergic effects
Bradycardia
Cardiogenic shock
Systolic pressure<90mmhg
Sick sinus syndrome
Left ventricle dysfunction

37
Q

What is sodium Nitroprusside

A

It is a potent vasodilator

38
Q

What are the preparations or types of sodium Nitroprusside

A

Nipride
Nitopress

39
Q

State the mechanism of action of sodium Nitroprusside

A

Directly relaxes arteriolar venous smooth muscles
|
Resulting in reduction of cardiac preload and afterload

40
Q

State the indication for sodium Nitroprusside

A

Hypertensive crisis
To reduce bleeding by creating hypotension during pregnancy

41
Q

State the contraindications of sodium Nitroprusside on maternal

A

Nausea
Vomiting
Severe hypotension
restlessness
Decrease reflexes
Loss of consciousness

Drugs Used In Pregnancy Labour Pueperium And Newborn πŸ’ŠπŸ’ŠπŸ’Š (11 decks)

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