Rheumatology: Fibromyalgia Flashcards
1
Q
Outline the pathogenesis of fibromyalgia
A
Disorder of central pain processing - chronic widespread pain
Induced by sleep deprivation - EEG shows reduced REM = hyper-activation in response to noxious stimulation + activation of brain regions associated with perception to non-painful stimuli
2
Q
What are the signs and symptoms of fibromyalgia?
A
joint/muscle stiffness profound fatigue unrefreshed sleep numbness headaches irritable bowel/bladder syndrome depression and anxiety poor concentration
3
Q
How is fibromyalgia managed?
A
Many pts improve on explanation of their symptoms
Measures to improve sleep and physical activity levels
Low dose amitriptyline
Pregabalin
CBT
