Rheumatology Flashcards
Temporal arteritis is more likely in patients with which condition?
polymyalgia rheumatica
X-ray features in rheumatoid arthritis
soft tissue swelling juxta-articular osteoporosis or osteopenia reduced joint space (late) bony erosions (late) subluxation (late) complete carpal destruction
features of ehler danlos
elastic, fragile skin
joint hypermobility: recurrent joint dislocation
easy bruising
aortic regurgitation, mitral valve prolapse and aortic dissection
subarachnoid haemorrhage
angioid retinal streaks
trying for a baby on methotrexate, what’s the advice?
Patients using methotrexate require effective contraception during and for at least 6 months after treatment both men and women
features of pseudogout
acutely extremely painful single large joint with swelling
test for lateral epicondylitis
Lateral epicondylitis: worse on resisted wrist extension/suppination whilst elbow extended
features of Bechet’s syndrome
autoimmune medicated inflammation of blood vessels
classically: 1) oral ulcers 2) genital ulcers 3) anterior uveitis
thrombophlebitis and deep vein thrombosis
arthritis
neurological involvement (e.g. aseptic meningitis)
GI: abdo pain, diarrhoea, colitis
erythema nodosum
Ankylosing spondylitis features - the ‘A’s
Apical fibrosis Anterior uveitis Aortic regurgitation Achilles tendonitis AV node block Amyloidosis
What is Felty’s syndrome?
rheumatoid arthritis, splenomegaly and neutropenia
Azathioprine and allopurinol severe interaction
bone marrow suppression
Features of reactive arthritis
develops within 4 weeks of initial infection
symptoms last 4-6 months
asymmetrical oligoarthritis of lower limbs
dactylitis
symptoms of urethritis
eye: conjunctivitis (seen in 10-30%), anterior uveitis
skin: circinate balanitis (painless vesicles on the coronal margin of the prepuce), keratoderma blenorrhagica (waxy yellow/brown papules on palms and soles)
X-ray findings in psoriatic arthritis
‘plantar spur’ and ‘pencil and cup’.
Methotrexate interactions
avoid prescribing trimethoprim or co-trimoxazole concurrently - increases risk of marrow aplasia
high-dose aspirin increases the risk of methotrexate toxicity secondary to reduced excretion
RA disease markers
RF, Anti-ccp
Dermatomyositis disease markers
ANA, Anti-Jo
