Rheumatology Flashcards
1
Q
Features of Limited Systemic Sclerosis
A
Includes CREST syndrome
- Calcinosis
- Raynaud’s
- Oeseophageal and gut dysmotility
- Sclerodactyly
- Telangiectasia
+ skin involvement limited to hands, feet and face
PHT in 15%
2
Q
Features of Dermatomyositis
A
Myositis+ skin involvement
Heliotrope rash Macular rash (shawl sign) Nailfold erythema Gottron's papule on knuckles, elbows and knees Mechanics hands
3
Q
Abs in SLE
A
ANA, dsDNA, Ro, La, Sm and RNP
4
Q
Abs in Sjogren’s
A
RF, ANA, Ro, La
5
Q
Abs in CREST
A
Centromere
6
Q
Abs in Drug induced lupus
A
Histone
7
Q
Abs in Systemic Sclerosis
A
Centromere: limited
Scl70/topoisomerase: diffuse
RNA pol 1, 2, 3: diffuse
8
Q
Abs in Poly- and Dermatomyositis
A
Jo-1
9
Q
Causes of drug induced lupus
A
Procainamide, phenytoin, hydralazine, isoniazid