Rheumatology Flashcards

1
Q

Features of Limited Systemic Sclerosis

A

Includes CREST syndrome

  • Calcinosis
  • Raynaud’s
  • Oeseophageal and gut dysmotility
  • Sclerodactyly
  • Telangiectasia

+ skin involvement limited to hands, feet and face
PHT in 15%

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2
Q

Features of Dermatomyositis

A

Myositis+ skin involvement

Heliotrope rash
Macular rash (shawl sign) 
Nailfold erythema 
Gottron's papule on knuckles, elbows and knees 
Mechanics hands
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3
Q

Abs in SLE

A

ANA, dsDNA, Ro, La, Sm and RNP

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4
Q

Abs in Sjogren’s

A

RF, ANA, Ro, La

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5
Q

Abs in CREST

A

Centromere

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6
Q

Abs in Drug induced lupus

A

Histone

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7
Q

Abs in Systemic Sclerosis

A

Centromere: limited
Scl70/topoisomerase: diffuse
RNA pol 1, 2, 3: diffuse

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8
Q

Abs in Poly- and Dermatomyositis

A

Jo-1

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9
Q

Causes of drug induced lupus

A

Procainamide, phenytoin, hydralazine, isoniazid

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