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Paediatrics > Rheumatology > Flashcards

Rheumatology Flashcards

1
Q

Arthritis in which joint is most suggestive of haemachromatosis ?

A

Metacarpophalangeal

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2
Q

Involvement of DIP joints is suggestive of which arthritis ?

A

Psoriatic

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3
Q

Which type of JIA is associated with asymptomatic chronic uveitis? And what’s the best test

A

Oligoarthritis

ANA

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4
Q

Which type of JIA is associated with asymptomatic chronic uveitis ?

A

Oligo

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5
Q

What is Felty syndrome ?

A

RF pos polyarthritis
Neutropenia
Splenomegaly

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6
Q 
What is the diagnosis? 
Daily spiking fever 
Salmon coloured rash 
Knee arthritis 
Hepatosplenomegaly
A

Systemic JIA

Do BMA

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7
Q

Which type of JIA is associated with acute symptomatic anterior uveitis?

A

Enthesitis related arthritis

HLA B27
Hips
Achilles tendinitis

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8
Q

What is the diagnosis?

Dactylitis and DIP arthritis ?

A

Psoriatic arthritis

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9
Q

What is the diagnosis ? What test to confirm ?
Posterior uveitis
Sterile pustules
Mouth ulcers

A

Behcet’s

Skin pathergy test

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10
Q 
What is the diagnosis 
What blood test to confirm ? 
Heliotrope rash 
Shawl sign 
Nail fold capillary changes
A 
Juvenile dermatomyositis 
CK 
AST 
ALT 
LDH 
Muscle biopsy
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11
Q 
What is the diagnosis 
Painless nasal ulcers 
Pericarditis
Haemolytic anaemia 
Positive ANA
A

SLE

Hydroxychloroquine

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12
Q

What test should you order for neonate presenting with complete AV block?

A 
ENA antibodies (Ro and La) 
Treat mother
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13
Q

What is the diagnosis

Morphea rash

A

Scleroderma

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14
Q 
What is the diagnosis 
What test to confirm? 
Pos ANA 
Pos RF 
Keratoconjunctivitis 
Parotitis
A

Sjogrens
Shirmers test - Rose Bengal staining
Salivary gland scintigraphy
Biopsy - lymphocytic sialedinitis

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15
Q 
What is the diagnosis? 
High fevers every 4 weeks 
Non exudative pharyngitis 
Oral ulcers 
Arthralgias 
Neg throat cultures
A

PFAPA

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16
Q

What is the mechanism of action of rituximab?

A

Anti CD 20 human/mouse monoclonal antibody

17
Q

What is the mechanism of action of Anakinra

A

Anti IL-1

18
Q

What is the mechanism of action of tociluzimab?

A

Anti IL-6

19
Q

What is the mechanism of action of Abatacept?

A

T cell co stimulatory modulator

Fusion protein CTLA 4 + human Ig

20
Q

What is the mechanism of action of adalimumab?

A

Anti TNF human monoclonal antibody

21
Q

What is the mechanism of action of infliximab

A

Anti TNF

22
Q

What is the mechanism of action of leflunomide?

A

Inhibits pyrimidine synthesis

23
Q

What is the mechanism of action of cyclosporine?

A

Inhibits calcineurin

Paediatrics (17 decks)

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