Rheumatology

Question 1

Tocilizumab

Answer 1

IL-6 antibody for RA and JIA

Question 2

Hemophagocytic Lymphohistiocytosis (HLH)

Answer 2

Fever, spleen enlargement, recurrent infections, high ferritin >500

Question 3

Three antiphospholipid antibodies

Answer 3

40% of SLE develop APS

1) anti-cardiolipin
2) anti-beta2-glycoprotein
3) lupus anticoagulant

Question 4

CREST syndrome acronym

Answer 4

Calcinosis
Raynauds
Esophageal dysmotility
Scleroderma
Telangiectasia

Anti-centromere antibody

Question 5

Behcet patient reaction after needlestick

Answer 5

Pathergy - excessive ulceration after mild injury

Question 6

Diseases associated with vitiligo

Answer 6

Thyroid
Addison’s
Type I dm
Lupus
Pernicious anemia

Question 7

CREST syndrome patients etiology of pHTN

Answer 7

Pulmonary arterial hypertension due to intimal smooth muscle hyperplasia (not the same as ILD)

Question 8

Felty syndrome

Answer 8

Rheumatoid arthritis
Splenomegaly
Neutropenia
Rheumatoid nodules
Vasculitic skin lesions 
40s show up

Question 9

GPA specific antibody

Answer 9

C-ANCA
And
Anti-proteinase 3

Question 10

Systemic sclerosis markers

Answer 10

Scl70
RNA polymerase III
ANA

Question 11

Rosacea vs SLE rash

Answer 11

SLE deeper red in color
SLE spares nasolabial folds
SLE not triggered by alcohol