Rheumatology Flashcards
Rheumatoid arthritis PC
ANNOYIN’ SCARS
Arthritis Nodules Nails and skin Ophthalmology lYmphadenopathy Immunocompromise Neurology Systemic Cardiac Respiratory Syndrome - Felty's Stills disease
DMARDs
SAMPLING
Sulphasalazine (oligospermia, headache, dizziness, rash)
Antimalarials - chloroquine/hydroxychloroquine (retinopathy, rash)
Methotrexate - purine antagonist (liver failure, lung fibrosis, acute pneumonitis, cytopenia)
Penicillamine - (glomerulonephritis, bronchiolitis, cytopenia, myosotis, taste disturbance)
Leflunomide - pyrimidine antagonist (hypertension, diarrhoea, liver impairment, cytopenia)
Infliximab or etanercept - TNF alpha antagonist (opportunistic infections eg fungal, TB, bacterial septicaemia
Nasty - azathioprine, mycophenolate, cyclophosphamide, cyclosporine (immunosuppression, cytopenia, lymphoma, haemorrhagic cystitis
Gold - IM or PO (nephrosis, renal failure, cytopenia, diarrhoea)
Lichen planus
planus: purple, pruritic, papular, polygonal rash on flexor surfaces.
