Cardiology Flashcards
Causes of aortic stenosis
CRABS (increasing age)
Congenital (congenital ring, HOCM, Williams syndrome)
Rheumatic fever (esp females and rheumatoid arthritis)
Atherosclerosis
Bicuspid AV calcification (40-60)
Senile calcific degeneration (60+)
Aortic stenosis - PC
Angina Arrhythmias LVH Exertional syncope Emboli - TIA/ stroke
Aortic stenosis - Ix
ECG, CXR, Echo, Catheter
Aortic stenosis - Rx and contraindicated drugs
Medical - statins, antiplatelet
Contraindicated meds - nitrates, ACE inhib., Ca antagonists
SBE prophylaxis
Surgical - Valvuplasty, valve replacement, myomectomy
Causes of aortic regurgitation
- Ring dilation -
a) pressure: hypertension, aortic dissection, trauma
b) Weak connective tissue eg ehlos danlos or marfans, syphilis, cor bovium - Cusp contraction -
a) infection: Rheum fever, infective endocarditis
b) autoimmune: seronegative arthropathies eg. ank spondylitis, Reiter’s
c) toxins: cabergoline, pergolide - Poor fitting
a) biscupid aortic valve disease
b) supracrital VSD
Aortic Regurgitation - PC
- Arrhythmias
- Emboli (from vegetation), TIA: amaurosis fugax, CVA
- Eccentric LVH, LVF, RVF
Aortic Regurgitation - Ix
ECG, CXR, Echo, Catheter
Aortic Regurgitation - Tx
Medical: Nifedipine (avoid in HF), ACE inhibitors
SBE prophylaxis
Surgical: valve replacement
Presentation of mitral stenosis
- Left atrial enlargement – AF, hoarseness, dysphasia, bronchiectasis
- emboli
- pulmonary oedema/recurrent respiratory tract infection
- pulmonary hypertension/RSH failure; ischaemia/cachexia
Mitral stenosis – investigations
ECG CXR echo catheter
Mitral stenosis – treatment
- Anticoagulate
- SBE prophylaxis
- surgical – closed valvotomy, open valvotomy, valve replacement
Causes of mitral regurgitation
a) Ring dilatation 1. LV dilatation (volume overload; AR, pressure overload; AS, HT)
2. Cardiomyopathy: HOCM, dilated, restrictive
3. Trauma/mechanical valve leak
b) Cusp contraction 1. infection e.g. rheumatic fever, SBE
2. Autoimmune e.g. RA, SLE, ankylosing spondylitis
3. ASD, primum
4. Senile calcification degeneration
c) subvalvular apparatus dysfunction e.g. MI, mitral valve prolapse (Marfan’s, VSD, polycystic kidney disease, straight back, ischaemic heart disease, neuroses/women)
Mitral regurgitation – PC
- AF
- pulmonary oedema/recurrent RTI
- pulmonary hypertension/RSH failure
- MVP PC – chest pain, palpitations, syncope, SOB, fatigue
Mitral regurgitation – Ix
ECG CXR echo catheter
Mitral regurgitation - Rx
Anticoagulate in AF, SBE prophylaxis, surgical valve replacement